Search Results - Vaccines

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Dog Flu Vaccine
A live-attenuated vaccine for canine influenza virus.Problem Solved by this TechnologyCanine influenza virus (CIV) is a recently emerged virus that causes acute respiratory disease in dogs. Most dogs have no immunity to CIV, and infection may therefore spread quickly in locations with concentrated dog populations such as boarding kennels, doggy day...
Published: 11/15/2018   |   Inventor(s): Luis Martinez-Sobrido, Aitor Nogales-Gonzalez, Colin Parrish
Keywords(s):  
Category(s): Vaccines
Improved Live Attenuated Flu Vaccine
Novel methodologies to engineer an improved and a more effective live attenuated flu vaccine.Problem Solved by this TechnologyCurrent flu vaccinations (injection-based inactivated influenza virus and recombinant influenza virus vaccines) are suboptimal as they generate limited cellular-mediated immune responses. Additionally, particularly vulnerabl...
Published: 10/13/2016   |   Inventor(s): Andrew Cox, Stephen Dewhurst
Keywords(s):  
Category(s): Vaccines
Vaccine against Pneumocystis and Streptococcal Infections
Novel polypeptides and immunogenic conjugates capable of inducing passive and active immunity against Pneumocystis carinii and Streptococcus pneumoniae infections.Problem Solved by this TechnologyPneumocystis pneumonia (PCP), caused by an opportunistic pathogen Pneumocystis carinii, is a significant cause of morbidity and mortality in immunocomprom...
Published: 9/21/2016   |   Inventor(s): Francis Gigliotti
Keywords(s):  
Category(s): Vaccines
Vaccine against Pneumocystis and Streptococcal Infections
Novel polypeptides and immunogenic conjugates capable of inducing passive and active immunity against Pneumocystis carinii and Streptococcus pneumoniae infections. Problem Solved by this TechnologyPneumocystis pneumonia (PCP), caused by an opportunistic pathogen Pneumocystis carinii, is a significant cause of morbidity and mortality in immunocompro...
Published: 9/21/2016   |   Inventor(s): Francis Gigliotti, Terry Wright, Constantine Haidaris, Patricia Simpson-Haidaris
Keywords(s): Antibody, Infectious Disease, Therapy
Category(s): Vaccines
Improved Safer Nasal Spray Flu Vaccines
A novel live attenuated influenza virus nasal vaccine safe enough for use by young children and asthmatics.Problem Solved by this TechnologyYoung children, pregnant women, and persons with compromised immune systems are at high risk for complications arising from an influenza infection. These people are currently served with sub-dermal, or nasal a...
Published: 3/26/2015   |   Inventor(s): Stephen Dewhurst, Andrew Cox, John Treanor, Baek Kim
Keywords(s):  
Category(s): Vaccines
Development of Arenavirus Vaccines through Codon Deoptimization
A novel strategy for developing live-attenuated arenavirus vaccines. Problem Solved by the TechnologyArenaviruses have a significant impact on public health and pose a credible threat to biodefense.There are four arenaviruses that cause severe hemorrhagic fever in humans (Lassa virus, endemic to Africa; and Machupo, Junin, and Guanarito viruses end...
Published: 3/24/2015   |   Inventor(s): Luis Martinez-Sobrido, Juan Carlos De La Torre
Keywords(s):  
Category(s): Vaccines
Inducing Immune Responses Using Platelets
Brief Description: The use of patients own dendritic cells pulsed with a specific antigen to induce T-cells responses and induction of memory T-cells is widely known as an approach for stimulating the immune system in individualized medicine. This approach entails isolation of monocytes from the blood (where their numbers are relatively low) ...
Published: 10/12/2012   |   Inventor(s): Craig Morrell
Keywords(s): Antibacterial, Antiviral, Cancer, Infection, Infectious Disease, Research Tool
Category(s): Vaccines, Therapeutic
Novel Human Papillomavirus (HPV) Chimeric Virus Like Particle (cVLP)-Based Gene Delivery System for Phrophylaxis and Immunotherapy of Infectious Diseases
Applications: As demonstrated in vitro and in vivo results, HPV VLPs, preferably chimeric HPV L1/L2 VLPs, are useful for facilitating delivery and expression of plasmid DNA to antigen presenting cells, and for enhanced induction of immune responses against co-administered plasmid DNA-based immunogens. Results also demonstrate enhanced immune re...
Published: 5/4/2009   |   Inventor(s): Robert Rose, Christine Malboeuf, Youngeun Ellen Lee Son, Christopher Lane
Keywords(s): Vaccine
Category(s): Vaccines
Stabilized Outersurface Protein A Fragment as a Lyme Disease Vaccine
ApplicationsLyme disease is a tick-borne infection caused by the spirochete Borrelia burgdorferi that can result in damages to joints, cardiovascular and nervous systems. Outsurface protein A (OspA) is a major surface antigen of Borrelia burgdorferi. Anti- OspA mAb has been shown to protect severe combined immunodeficiency mice from clinical sympto...
Published: 5/4/2009   |   Inventor(s): Shohei Koide, Benjamin Luft, John Dunn, Catherine Lawson
Keywords(s): Vaccine
Category(s): Vaccines
Transcutaneous Immunization Against Papillomavirus Disease
Brief Description: This invention is a method of vaccinating against human papillomavirus (HPV) by using papillomavirus ?virus-like particles? transcutaneously to induce an immune response to the virus. Applications: Papiloma viruses constitute a group of DNA viruses that induce both lytic infections and either benign or malignant tumors. Pap...
Published: 5/4/2009   |   Inventor(s): Robert Rose
Keywords(s): Vaccine
Category(s): Vaccines
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