Latest technologies from University of Rochesterhttp://rochester.technologypublisher.comBe the first to know about the latest inventions and technologies available from University of Rochesteren-USWed, 28 Jun 2017 01:54:34 GMTMon, 01 May 2017 12:43:02 GMThttp://blogs.law.harvard.edu/tech/rssdavid_englert@urmc.rochester.eduCopyright 2017, University of RochesterSmall Molecule Anti-Scarring Agentshttp://rochester.technologypublisher.com/technology/25194Mon, 01 May 2017 12:43:02 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/251946-Bromoindirubin-3'-oxime Promotes Human Mesenchymal Stem Cell Proliferation, Stem Cell Phenotype, and Population Homogeneityhttp://rochester.technologypublisher.com/technology/24610Thu, 16 Mar 2017 11:53:03 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/24610Early Detection of and Treatment for Neurodegenerative Diseaseshttp://rochester.technologypublisher.com/technology/23379Thu, 20 Oct 2016 13:42:04 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/23379Improved Live Attenuated Flu Vaccinehttp://rochester.technologypublisher.com/technology/23207Thu, 13 Oct 2016 13:32:07 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/23207Vaccine against Pneumocystis and Streptococcal Infectionshttp://rochester.technologypublisher.com/technology/22885Wed, 21 Sep 2016 11:46:47 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/22885Vaccine against Pneumocystis and Streptococcal Infectionshttp://rochester.technologypublisher.com/technology/22884Wed, 21 Sep 2016 11:46:46 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/22884Needle-Free Drug/Vaccine Delivery Systemhttp://rochester.technologypublisher.com/technology/22770A novel peptide-based strategy for controlled transepithelial delivery of therapeutic molecules. Problem Solved by this TechnolgyTransdermal drug delivery systems (TDDS) are increasingly becoming an attractive alternative to the oral route as this method can avoid first pass effects, can provide steady drug plasma levels and is poised to replace painful hypodermic injections. Intact skin acts as a natural barrier and can impede transdermal delivery of therapeutic agents. Existing TDDS deliver only small molecule drugs and cannot be used for larger therapeutic agents such as antibodies and vacc...Thu, 01 Sep 2016 05:48:37 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/22770A Novel Approach to Treatment of Hyperglycemia Using a Nano-Particle-Encapsulated Peptidehttp://rochester.technologypublisher.com/technology/22510Thu, 21 Jul 2016 11:15:42 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/22510The Charcot-Marie-Tooth Disease Health Index (CMT-HI)http://rochester.technologypublisher.com/technology/22384 The CMT-Health Index (CMT-HI) is a disease-specific, patient-reported, outcome measure designed to reliably and responsively measure therapeutic benefit in Charcot-Marie-Tooth disease (CMT) clinical trials. The CMT-HI may also be used to measure overall patient health in a clinical setting. It covers the 18 areas of greatest importance to the adult CMT population and has been designed to satisfy recommendations from the FDA for use in drug labeling claims. Applications The CMT-HI is capable of both classifying patients with inherited neuropathies and measuring clinically-relevant change in di...Thu, 30 Jun 2016 13:09:09 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/22384The Myotonic Dystrophy Health Index (MDHI) Italian Versionhttp://rochester.technologypublisher.com/technology/22383 The Myotonic Dystrophy Health Index (MDHI) Italian Version is a survey designed to efficiently measure the overall level of disease burden in a patient with myotonic dystrophy type-1 whose native language is Italian. This disease-specific patient-reported outcome measure is designed is designed to reliably and responsively measure therapeutic benefit in myotonic dystrophy clinical trials. It may also be used to measure overall patient health in a clinical setting. It covers the 17 areas of greatest importance to the adult myotonic dystrophy population. The MDHI is a disease-specific, patient ...Thu, 30 Jun 2016 13:09:09 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/22383The Myotonic Dystrophy Health Index Short Form (MDHI-SF)http://rochester.technologypublisher.com/technology/22382Thu, 30 Jun 2016 13:09:08 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/22382Congenital and Childhood Myotonic Dystrophy Research Survey: Instrument for Children Ages 5 to 7http://rochester.technologypublisher.com/technology/22381Thu, 30 Jun 2016 13:08:54 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/22381Congenital and Childhood Myotonic Dystrophy Health Index: Instrument for Children Ages 8 to 11http://rochester.technologypublisher.com/technology/22380Thu, 30 Jun 2016 13:08:53 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/22380Congenital and Childhood Myotonic Dystrophy Health Index: Instrument for Children Ages 12 to 17http://rochester.technologypublisher.com/technology/22379Thu, 30 Jun 2016 13:08:52 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/22379Congenital and Childhood Myotonic Dystrophy Health Index: Parent Proxy Instrumenthttp://rochester.technologypublisher.com/technology/22378Thu, 30 Jun 2016 13:08:51 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/22378Peptide Therapy for Inflammatory Bowel and Celiac Diseaseshttp://rochester.technologypublisher.com/technology/22192Mon, 06 Jun 2016 07:59:20 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/22192The Rochester Digital Cloakhttp://rochester.technologypublisher.com/technology/21990Thu, 19 May 2016 07:33:11 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/21990Method for Diagnosis and Treatment of Idiopathic Pulmonary Fibrosis via Detecting and Inhibiting Histone Methylation and Associated Proteinshttp://rochester.technologypublisher.com/technology/21976Wed, 18 May 2016 11:18:25 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/21976Treatment for Female Infertilityhttp://rochester.technologypublisher.com/technology/21737 A novel treatment for a variety of conditions resulting in female infertility. Problem Solved by this Technology Anti-Müllerian hormone (AMH) acts as a natural follicular gatekeeper limiting follicle growth initiation and maintains the primordial follicle pool during reproductive years. AMH is also an intra-ovarian regulator that inhibits follicular atresia at later stages of follicle development. Thus, low AMH levels lead to more rapid follicle loss contributing to pathophysiological conditions called diminished ovarian reserve (DOR) and premature ovarian failure (also known as premature ova...Tue, 12 Apr 2016 11:43:38 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/21737Cheap, Plentiful, and Environmentally Friendly Method for Producing Hydrogenhttp://rochester.technologypublisher.com/technology/21735Tue, 12 Apr 2016 11:29:13 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/21735Production of High Molecular Weight Hyaluronic Acidhttp://rochester.technologypublisher.com/technology/19881Thu, 02 Jul 2015 11:04:41 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/19881Device to Determine the Location of the Guidewire in Lumpectomy Excisionshttp://rochester.technologypublisher.com/technology/19012Tue, 28 Apr 2015 13:44:30 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/19012Light-Controlled Immunotherapyhttp://rochester.technologypublisher.com/technology/18988 A novel therapy using light-activated chemokine receptors to direct specific lymphocytes to desired locations within a patient's body. Problem Solved by the Technology Most current cancer treatments are delivered systemically,and are usually associated with undesirable side-effects, including nausea, hair loss, and weakness. Applications Dr. Minsoo Kim at the University of Rochester has engineered the means to direct ex vivo-generated immune-promoting or tolerogenic T cells either to enhance immunity or to promote adoptive cell transfer therapies in patients. By applying this methodology to ...Mon, 27 Apr 2015 10:47:42 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/18988Improved Safer Nasal Spray Flu Vaccineshttp://rochester.technologypublisher.com/technology/18806Thu, 26 Mar 2015 12:43:50 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/18806Development of Arenavirus Vaccines through Codon Deoptimizationhttp://rochester.technologypublisher.com/technology/18775 A novel strategy for developing live-attenuated arenavirus vaccines. Problem Solved by the TechnologyArenaviruses have a significant impact on public health and pose a credible threat to biodefense.There are four arenaviruses that cause severe hemorrhagic fever in humans (Lassa virus, endemic to Africa; and Machupo, Junin, and Guanarito viruses endemic to South America). A fifth arenavirus, lymphocytic choriomeningitis virus (LCMV), is found throughout the world and it is particularly troublesome for immunocompromised individuals. Safe and effective arenavirus vaccines have remained elusiv...Tue, 24 Mar 2015 14:07:15 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/18775Preoperative Planning Document To Facilitate Correlation of IVUS and CT Scan Measurements For Placement Of IVUS-Guided IVC Filtershttp://rochester.technologypublisher.com/technology/18445 Preoperative planning document for the single puncture intravasular ultrasound (IVUS) guided bedside placement of IVC filters. Application Pulmonary Embolism (PE) has been reported in over 350,000 patients per year, with an estimated annual mortality rate of 240,000. Vena cava filtration is being used as an effective means of prophylaxis against PE in post-operative and critically ill patients. A safe and cost-effective method of placing the filters is through single puncture intravasular ultrasound (IVUS) guided bedside placement which eliminates risk of patient transport and exposure to int...Mon, 09 Mar 2015 08:51:04 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/18445The Depth Advancement Marker Needle for Image Guided Injections (DAMNIGI)http://rochester.technologypublisher.com/technology/18444Mon, 09 Mar 2015 08:51:02 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/18444A Non-Contact ECG System Employing Artifact Compensationhttp://rochester.technologypublisher.com/technology/18443Mon, 09 Mar 2015 08:50:59 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/18443Manufacture of Regularly Shaped Polymer Cholesteric Liquid Crystal Flakes with a Mechanically Flexible Moldhttp://rochester.technologypublisher.com/technology/17796Applications: This invention relates to manufacturing micron-sized shaped flakes of plastic (flowable) material which have precise configurations, and particularly to making flakes of polymeric liquid crystal materials to be used in a host fluid in electrically addressable optical devices for information displays. Advantages: Micron sized PCLC flakes that are more regularly shaped behave with more uniform motion within an electro-optic cell. Current freeze fracture methods used to manufacture polymer cholestric liquid crystal flakes result in arbitrary shapes. This invention, however, uses m...Wed, 07 Jan 2015 10:20:31 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/17796Novel Endotracheal Tube (ET) Securementhttp://rochester.technologypublisher.com/technology/17661Wed, 10 Dec 2014 08:44:23 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/17661All-in-One Mix and Inject Prefillable Syringe Systemhttp://rochester.technologypublisher.com/technology/17580Thu, 20 Nov 2014 07:55:23 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/17580Perfect Paraxial Cloak Design and Devicehttp://rochester.technologypublisher.com/technology/16021Wed, 01 Oct 2014 09:07:15 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/16021Treating and Monitoring Rheumatoid Arthritis with PDE5 Inhibitorshttp://rochester.technologypublisher.com/technology/15865A safe and effective treatment for Rheumatoid arthritis using approved drugs. Problem Solved by this Technology Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disorder that causes episodic waves of pain, swelling, stiffness, and loss of function in joints and surrounding tissues. It is estimated that 0.5 - 1% of the population is affected with RA. Available drugs either alleviate symptoms or slow the disease progression, but there is currently no cure for RA. Additionally, the high cost of biologics (TNF inhibitors) limits patient access and leaves a large portion of t...Fri, 12 Sep 2014 08:09:45 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/15865Tunable Shape Memory Polymershttp://rochester.technologypublisher.com/technology/15808Wed, 03 Sep 2014 07:48:15 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/15808A Low Cost Device for the Detection of Prostate Cancer in Real Timehttp://rochester.technologypublisher.com/technology/15807Wed, 03 Sep 2014 07:45:22 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/15807Treatment for Hyperammonemic Encephalopathy and Seizureshttp://rochester.technologypublisher.com/technology/15685Thu, 07 Aug 2014 13:02:16 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/15685Novel Small Molecules to Treat Alzheimer’s Diseasehttp://rochester.technologypublisher.com/technology/15669Tue, 05 Aug 2014 07:25:25 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/15669Heavy Atom Labeled acyl-CoAhttp://rochester.technologypublisher.com/technology/15651 A novel protocol to produce large quantities of nearly 100% homogenous heavy-labeled acyl-CoAs rapidly and inexpensively. Problem Solved by this Technology Individual heavy atom-labeled acyl-CoAs are currently available made-to-order through several companies or are being generated in-house in labs as needed. The production of a full battery of acyl-CoAs is currently achieved using mammalian cells in a tedious and expensive process (that requires ~10 weeks and thousands of dollars in reagents). Researchers at the University of Rochester and the University of Pennsylvania have developed an alt...Mon, 04 Aug 2014 10:48:00 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/15651Protease Activated Cytokines as Anti-Cancer Therapyhttp://rochester.technologypublisher.com/technology/15582Mon, 21 Jul 2014 13:08:59 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/15582Novel Method to Prevent or Treat Fibrosishttp://rochester.technologypublisher.com/technology/15542 A novel method for treating and preventing fibrosis and fibrosis-related conditions using fibronectin binding proteins and polypeptides. Problem Solved by the Technology Fibrosis is the formation of excess fibrous connective tissue in an organ or tissue that can alter the architecture and compromise the function of that organ or tissue. Fibrosis usually occurs as a result of injury and inflammation, and can present itself in different tissues. Examples include lungs (pulmonary fibrosis, idiopathic pulmonary fibrosis, cystic fibrosis), liver (including cirrhosis), heart (myocardial fibrosis...Thu, 17 Jul 2014 11:27:57 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/15542Extensively Self-Renewing Erythroblasts (ESRE)http://rochester.technologypublisher.com/technology/15221This technology provides a human cell population that can self-renew extensively and yet retain the capacity to differentiate into red blood cells (RBCs). These cells are referred to as extensively self-renewing erythroblasts (ESREs). The ESREs can serve as a renewable source of transfusable RBCs.Mon, 19 May 2014 12:29:13 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/15221Novel Synthetic Lung Surfactant Peptideshttp://rochester.technologypublisher.com/technology/15219 A novel synthetic lung surfactant for the treatment of neonatal and acute respiratory distress syndromes. Problem Solved by the TechnologyLung surfactant replacement therapy is commonly used on premature infants with neonatal respiratory distress syndrome (NRDS). NRDS, caused by a lack of surfactant, occurs in 10% of premature babies (1% of all newborns) and is the leading cause of death in premature babies. Research has shown that surfactant therapy can also help to reverse surfactant dysfunction in acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). ALI and...Fri, 16 May 2014 13:16:08 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/15219Novel Preventative Anti-caries and Periodontal Diseases Treatmenthttp://rochester.technologypublisher.com/technology/15168Fri, 09 May 2014 12:53:34 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/15168A Method of Remyelinating Congenitally Dysmyelinated Forebrainshttp://rochester.technologypublisher.com/technology/15069Thu, 17 Apr 2014 12:51:35 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/15069RNA Therapeutics for Diseases Caused by Nonsense Mutationshttp://rochester.technologypublisher.com/technology/15020Thu, 10 Apr 2014 07:28:09 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/15020Macrocyclic Peptidomimetics for Alpha-Helix Mimicryhttp://rochester.technologypublisher.com/technology/15015Wed, 09 Apr 2014 11:15:19 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/15015Methods and Compositions for Ribosomal Synthesis of Macrocyclic Peptideshttp://rochester.technologypublisher.com/technology/15014Wed, 09 Apr 2014 11:15:13 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/15014Methods and Compositions for the Preparation of Conformationally Constrained Peptide-Containing Moleculeshttp://rochester.technologypublisher.com/technology/15012Wed, 09 Apr 2014 11:14:56 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/15012Methods for Identifying, Diagnosing, and Predicting Survival of Lymphomashttp://rochester.technologypublisher.com/technology/15011The present invention discloses methods for identifying, diagnosing, and predicting survival in a lymphoma or lymphoproliferative disorder on the basis of gene expression patterns. The invention discloses a novel microarray, the Lymph Dx microarray, for obtaining gene expression data from a lymphoma sample. The invention also discloses a variety of methods for utilizing lymphoma gene expression data to determine the identity of a particular lymphoma and to predict survival in a subject diagnosed with a particular lymphoma. This information is useful in developing the appropriate therapeutic ap...Wed, 09 Apr 2014 11:14:51 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/15011Survival Predictor For Diffuse Large B Cell Lymphomahttp://rochester.technologypublisher.com/technology/15010 This invention provides methods and arrays related to a gene expression-based survival predictor for DLBCL patients, including patients treated with the current standard of care, which includes chemotherapy and the administration of Rituximab. The invention provides a method of predicting the survival outcome of a subject suffering from diffuse large B cell lymphoma (DLBCL) that includes obtaining a gene expression profile from one or more DLBCL biopsy samples from the subject. The gene expression profile, which can be derived from gene expression product isolated from the one or more biopsy ...Wed, 09 Apr 2014 11:14:51 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/15010A New Biomarker to Predict Patient Response to Anti-TNF Therapyhttp://rochester.technologypublisher.com/technology/14706Thu, 06 Mar 2014 11:51:41 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/14706A Vaccine Against Type 1 Diabeteshttp://rochester.technologypublisher.com/technology/14594 A novel vaccine to protect against type 1 diabetes. Problem Solved by the Technology Type 1 diabetes (once known as "juvenile diabetes") is usually detected in children and young adults. It occurs when the pancreas stops producing insulin, the body?s mechanism for converting starch and glucose into energy. This condition is serious and requires continuous monitoring and a life-long regimen of proper diet, exercise, and insulin injections. This course of treatment is difficult to comply with, and carries with it major adverse side-effects. Current immunomodulatory clinical trials failed to a...Thu, 27 Feb 2014 08:41:25 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/14594Antigenic Mimics of Discontinuous HIV-1 Envelope Epitopes Recognized by Broadly Neutralizing Antibodieshttp://rochester.technologypublisher.com/technology/13921Fri, 15 Nov 2013 09:34:10 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/13921The Fascioscapulohumeral Muscular Dystrophy Health Index (FSHDI)http://rochester.technologypublisher.com/technology/13491 The Fascioscapulohumeral Muscular Dystrophy Health Index (FSHDI) is a disease-specific, patient reported outcome measure for FSHDI. Each question in the FSHDI was selected based on its relevance to a large muscular dystrophy population, its ability to be consistently understood by patients, its reliability during test-retest evaluation, its content validity, its face validity, its construct validity, and its responsiveness in detecting therapeutic change. FDA guidelines were implemented during instrument development in order to allow the FSHDI to be utilized to support drug labeling claims. T...Wed, 09 Oct 2013 06:39:08 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/13491Parthenolide Derivatives, Methods for Their Preparation and Their Use as Anticancer Agentshttp://rochester.technologypublisher.com/technology/13346Tue, 27 Aug 2013 07:03:07 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/13346Artemisinin Derivatives, Methods For Their Preparation And Their Use As Antimalarial Agentshttp://rochester.technologypublisher.com/technology/13345Tue, 27 Aug 2013 07:03:03 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/13345Methods and Reagents for Site-Specific Labeling of Peptides and Proteinshttp://rochester.technologypublisher.com/technology/13344 Brief Description: Methods for site-specific protein functionalization find a broad range of applications in the context of protein detection, imaging, and purification, in the development of improved protein-based therapeutics (e.g. via PEGylation), and in the preparation of protein microarrays. This invention describes a new chemical method for site-specifically labeling a target protein at its C-terminus with an organic molecule of interest, such as a fluorescent dye, an affinity tag, a polymer, a drug molecule, etc. This methodology involves the use of novel reagents that can eff...Tue, 27 Aug 2013 07:03:01 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/13344Methods and Systems for Predicting the Reactivity of Mono-Oxygenase Enzymeshttp://rochester.technologypublisher.com/technology/13343 Applications This technology provides methods for rapidly finding selective and highly active P450-based oxidation catalysts for the oxyfunctionalization (i.e. hydroxylation, epoxidation) of a target organic molecule. This method is particularly useful for developing synthetic procedures that enable the functional elaboration of a high-value compound (e.g. natural product, lead compound, drug molecule) at poorly reactive or unreactive C?H sites. Accordingly, these methods can be useful in drug discovery and development campaigns toward obtaining analogs of a molecule of interest that possess ...Tue, 27 Aug 2013 07:02:59 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/13343SURUS: Super-Resolution Ultrasound Imaginghttp://rochester.technologypublisher.com/technology/12937Fri, 21 Jun 2013 05:55:01 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/12937Real Time Blood Pressure Monitor and Aneurism Monitorhttp://rochester.technologypublisher.com/technology/12714Fri, 07 Jun 2013 07:02:35 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/12714Measuring Interdisciplinary Team Performance in a Long-Term Care Settinghttp://rochester.technologypublisher.com/technology/12411Brief description: Theory-based, reliable, and valid measures of interdisciplinary teamwork have long been considered desirable and useful in explaining patient outcomes and in assisting with quality-of-care improvement efforts. This technology is a survey tool used to assess interdisciplinary team performance in a long-term care setting and to measure team performance in the Program of All-Inclusive Care for the Elderly (PACE). Tue, 30 Apr 2013 12:28:59 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/12411The Myotonic Dystrophy Health Index (MDHI)http://rochester.technologypublisher.com/technology/12222Fri, 22 Mar 2013 12:59:14 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/12222Isolating and Purifying Neuronal Stem Cells for Enrichment and Therapeutic Applicationshttp://rochester.technologypublisher.com/technology/12009Tue, 12 Mar 2013 08:12:39 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/12009Integrated Microfluidic Bubble Bioreactor for Cell Capturehttp://rochester.technologypublisher.com/technology/11984Tue, 05 Mar 2013 07:42:47 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/11984Health Promotion and Disease Prevention: Action for Healthhttp://rochester.technologypublisher.com/technology/11982 Brief Description: The technology disclosed herein is an online tutorial and course designed for health promotion and disease prevention.Tue, 05 Mar 2013 07:42:44 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/11982Catheterless Shunt System for Communicating Hydrocephalus and Other Trapped Body Fluidshttp://rochester.technologypublisher.com/technology/11969Brief Description: This novel, minimally invasive, device is a shunting system for the diversion of cerebrospinal fluid (CSF) that does not use catheters or tubing. This catheterless system provides direct CSF diversion out of the central nervous system, dramatically decreasing revision rate since catheter clogging remains the most common reason for failure. Applications: This invention relates to the treatment of hydrocephalus or for pressure relief secondary to trapped fluid in any body cavity. Hydrocephalus alone accounts for over 40,000 operations performed annually in the US. Medi...Fri, 01 Mar 2013 08:52:37 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/11969AGES (Academic Graphic Education System)http://rochester.technologypublisher.com/technology/11968Fri, 01 Mar 2013 08:52:32 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/11968Breastfeeding Quick Reference Guidehttp://rochester.technologypublisher.com/technology/11967Fri, 01 Mar 2013 08:52:30 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/11967Nanostructured Metal Surfaces for DNA Microarrayshttp://rochester.technologypublisher.com/technology/11965Fri, 01 Mar 2013 08:52:14 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/11965A Multi-function, Multi-purpose RF Ablation Catheterhttp://rochester.technologypublisher.com/technology/11665Applications: This invention aims at minimizing the number of steps required during intra-cardiac radio-frequency ablation, thereby reducing risk and complications. Current procedures require several exchanges of devices in and out of the vascular system, which requires time but also exposes the patient to risks such as vascular injury and introduction of air into the circulatory system. Advantages: This novel device system would save crucial time, expense and potential complications. It would help significantly reduce the number of steps, the need for extended periods of fluoroscopy an...Thu, 20 Dec 2012 10:25:47 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/11665Deep Brain Magnetic Stimulatorhttp://rochester.technologypublisher.com/technology/11564Thu, 29 Nov 2012 09:00:57 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/11564Vascular Closure Device (VCD) for Closing Arterial and Venous Access Sites from Procedures Using Sheaths 10 French or Greaterhttp://rochester.technologypublisher.com/technology/11313Fri, 12 Oct 2012 11:49:22 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/11313Controlling Collagen Microstructure with Ultrasoundhttp://rochester.technologypublisher.com/technology/11312 Brief Description: The invention use ultrasound to non-invasively and site-specifically control collagen fiber microstructure within three-dimensional (3D) engineered tissues. Applications: The invention can be developed for generating engineered tissues with spatial variations in mechanical strength, which could be useful for fabricating striated tissues, such as tendon and ligament; producing an artificial skin product with enhanced mechanical strength; and producing layered tissues, such as articular cartilage. Also, this technology can be applied for developing engineered tissu...Fri, 12 Oct 2012 11:49:21 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/11312Inducing Immune Responses Using Plateletshttp://rochester.technologypublisher.com/technology/11311 Brief Description: The use of patients own dendritic cells pulsed with a specific antigen to induce T-cells responses and induction of memory T-cells is widely known as an approach for stimulating the immune system in individualized medicine. This approach entails isolation of monocytes from the blood (where their numbers are relatively low) and their differentiation into dendritic cells over many days in cell culture. Therefore, this process is labor intensive, requires large blood volumes and makes contamination a potential major problem limiting the use of this approach as com...Fri, 12 Oct 2012 11:49:17 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/11311Novel Treatment for Hydrocephalushttp://rochester.technologypublisher.com/technology/11156 Brief Description: Ventricular cerebrospinal fluid (CSF) shunting remains the most prominent treatment of choice. CSF shunting procedures provide a rapid means to normalize intracranial pressure and can prevent brain damage. In the U.S. there are approximately 69,000 annual hospital admissions for hydrocephalus resulting in over 40,000 shunting procedures and costing over one billion dollars. The excessive costs predominantly arise from relatively high complication and revision rates as well as costly equipment. This novel device and technique help avoid complications and associat...Tue, 25 Sep 2012 13:01:05 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/11156Streamlined Analysis of Cancer Stem Cells in vitrohttp://rochester.technologypublisher.com/technology/11154Tue, 25 Sep 2012 13:00:51 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/11154Fibronectin Matrix Mimeticshttp://rochester.technologypublisher.com/technology/11153Tue, 25 Sep 2012 13:00:32 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/11153Ultrasound Technology to Control the Spatial Organization of Cells and Proteins in Engineered Tissueshttp://rochester.technologypublisher.com/technology/11152 Applications: This technology provides a method for using ultrasound standing wave fields for the non-invasive control of the spatial organization of the cells and proteins during the fabrication of three-dimensional engineered tissues. The organization of the cells in the artificial tissues can regulate key cellular functions such as growth, migration and vessel formation. Additionally, the method allows for greater mechanical strength of the engineered tissue by organizing the cells and proteins into planar bands. These features may allow for the production of engineered tissues for...Tue, 25 Sep 2012 13:00:23 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/11152Implantable Real-Time Monitor for Strokes and Post Traumatic Brain Injury Complicationshttp://rochester.technologypublisher.com/technology/9846 Brief Description: Real-time monitoring for strokes and post traumatic brain injury complications would provide early warning for timely intervention. Current methods of CT angiography or the use of the Licox probe are impractical for continuous monitoring, especially in moving subjects. Applications: This invention relates to an implantable device for continuous monitoring of post-stroke patients to prevent recurrent strokes. It would also allow monitoring for any complications following traumatic brain injury. Treatment for stroke is more time sensitive but less dramatic on pr...Thu, 19 Jul 2012 08:26:28 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/9846Methods of Studying Human and Non-Human Epidermalhttp://rochester.technologypublisher.com/technology/9845Thu, 19 Jul 2012 08:26:25 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/9845Simple NDSR Analysis Comparison Tool (SNAC)http://rochester.technologypublisher.com/technology/9841Thu, 19 Jul 2012 08:26:22 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/9841New Therapeutic Treatment for Multiple Myeloma and Lymphomahttp://rochester.technologypublisher.com/technology/9840Thu, 19 Jul 2012 08:26:21 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/9840SILO Support Brackethttp://rochester.technologypublisher.com/technology/9839Thu, 19 Jul 2012 08:26:20 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/9839Integrated Multi-criteria Decision Support Frameworkhttp://rochester.technologypublisher.com/technology/9838Thu, 19 Jul 2012 08:26:18 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/9838Patient Information Forms for FSHD (Facioscapulohumeral Muscular Dystrophy), DM (Myotonic Dystrophy), and Unaffected Blood Relatives of Individuals with FSHD or DMhttp://rochester.technologypublisher.com/technology/9837Thu, 19 Jul 2012 08:26:16 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/9837Methods For Determining The Presence Or Risk Of Developing Facioscapulohumeral Dystrophy (FSHD)http://rochester.technologypublisher.com/technology/9835Thu, 19 Jul 2012 08:26:15 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/9835Physician Checklists for FSHD (Facioscapulohumeral Muscular Dystrophy) and DM (Myotonic Dystrophy)http://rochester.technologypublisher.com/technology/9833Thu, 19 Jul 2012 08:26:13 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/9833Cognitive Testing Modelhttp://rochester.technologypublisher.com/technology/9832Thu, 19 Jul 2012 08:26:12 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/9832Blood Procedures Operations Manualhttp://rochester.technologypublisher.com/technology/9831Thu, 19 Jul 2012 08:26:11 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/9831IMMpattern - Immune Profiling Visualization Softwarehttp://rochester.technologypublisher.com/technology/9827Thu, 19 Jul 2012 08:26:07 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/9827ADTools 2.0http://rochester.technologypublisher.com/technology/9826Thu, 19 Jul 2012 08:26:06 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/9826ImageMarkhttp://rochester.technologypublisher.com/technology/9823 This invention is software that enhances the usability of Lucid Inc. for the purpose of using their Vivascope devices for assessment of Meissner Corpuscle density as a measure of sensory neuropathies. Applications: This software has significantly enabled quantization of Meissner Corpuscles by markedly decreasing the time required for assembly of images for Meissner corpuscles analysis and also by simplifying and semi-automating counts and morphologic and morphometric assessments of Meissner Corpuscles. This software will enable Meissner corpuscle density assessment as a measure of various s...Thu, 19 Jul 2012 08:26:02 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/9823Breastfeeding Factshttp://rochester.technologypublisher.com/technology/9822Thu, 19 Jul 2012 08:26:00 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/9822Introduction to Toxicologyhttp://rochester.technologypublisher.com/technology/9818Thu, 19 Jul 2012 08:25:50 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/9818Electrical Model of the Brainhttp://rochester.technologypublisher.com/technology/9817Thu, 19 Jul 2012 08:25:49 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/9817Unique DNA Probes for the Diagnosis of Methicillin-Resistance in Staphylococcus Aureushttp://rochester.technologypublisher.com/technology/9815Thu, 19 Jul 2012 08:25:16 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/9815Strong Vision Equation for Enhanced Zyoptix Outcomehttp://rochester.technologypublisher.com/technology/9814Thu, 19 Jul 2012 08:25:12 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/9814Manipulating mRNA Decay Pathway to Regulate Gene Expressionhttp://rochester.technologypublisher.com/technology/8934Fri, 02 Mar 2012 10:43:18 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/8934Faculty Productivity Programhttp://rochester.technologypublisher.com/technology/8879Mon, 13 Feb 2012 13:03:53 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/8879Fenestrated Venous Endografthttp://rochester.technologypublisher.com/technology/8089Fri, 28 Oct 2011 06:30:01 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/8089Urethral Stump Robotic Pro-tractor (USRP)http://rochester.technologypublisher.com/technology/7987Wed, 12 Oct 2011 13:14:33 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/7987Guidelines to Document and Manage Core Measure Conditionshttp://rochester.technologypublisher.com/technology/7984Wed, 12 Oct 2011 13:14:28 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/7984Integrated Microfluidic Bubble Bioreactor for Cell Capturehttp://rochester.technologypublisher.com/technology/7911Wed, 28 Sep 2011 07:38:25 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/7911RNA Modification to Modulate Telomerase Activityhttp://rochester.technologypublisher.com/technology/7701Mon, 01 Aug 2011 11:33:28 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/7701Anti-fungal Therapy Using a Combined Drugs Protocolhttp://rochester.technologypublisher.com/technology/7700 Many immunocompromised patients suffer from pulmonary and central nervous system fungal infections caused by pathogens such as C. neoformans. The current standard treatment entails intravenously administrating anti-fungal agents that are extremely toxic. In addition, new structural and mechanistic classes of antifungal therapeutics are needed to improve treatment options and to counter increasing resistance to currently used agents. This invention identifies and validates a novel treatment regime entailing a combination of two drugs. Applications: Dr. Damian Krysan of the URMC has fo...Mon, 01 Aug 2011 11:33:27 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/7700Biliverdin Reductase (BVR) Peptides That Inhibit PCK-delta for the Potential Treatment of Cancer and Inflammationhttp://rochester.technologypublisher.com/technology/7641 Applications: Dr. M. Maines is a leading expert in BVR research and has uncovered many applications for this enzyme. In this invention she has linked BVR to modulation of PKC and found potent inhibitory peptides that may have utility in both understanding and treating cancer. A multiplicity of functions has been ascribed to PKC. Recurring themes are that PKC is involved in receptor desensitization, in modulating membrane structure events, in regulating transcription, in mediating immune responses, in regulating cell growth, and in learning and memory. These functions are achieved by ...Fri, 22 Jul 2011 13:46:31 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/7641Conflict of Interest (COI)http://rochester.technologypublisher.com/technology/7199Brief Description: A web-based tool to assess and mitigate conflict of interest in collected and reported data. Applications: Conflict of Interest (COI) is a secured, internal, web-based tool designed to allow the manipulation, collection and management of any reported data that may potentially be considered a conflict of interest. The logic built-in can be altered for collection based questions. The technology is built around a three layer architecture that includes an interface, database, and business logic layer. Thu, 26 May 2011 12:03:40 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/7199Technology Abuse Scale (TAS)http://rochester.technologypublisher.com/technology/7198Thu, 26 May 2011 12:03:39 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/7198Simple, Accurate, Real-Time 3D Imaging Systemhttp://rochester.technologypublisher.com/technology/7194Thu, 26 May 2011 12:03:35 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/7194A Novel Approach to S.mutans Diagnostics, Therapeutic Intervention and Vaccineshttp://rochester.technologypublisher.com/technology/7192 Brief Description: Streptococcus mutans (S.mutans) is a major pathogen commonly found in the human oral cavity and is associated with dental caries. Dissemination of oral bacteria into the bloodstream is very common in patients subjected to dental procedures. S.mutans, if presents in the bloodstream, is suspected as a leading causative agent of cardiovascular diseases (CVD) such as infective endocarditis (IE), a life-threatening inflammation of the heart valves. Recently it has been shown that S. mutans is the most prevalent bacterial species in heart vegetations and atheromatous pl...Thu, 26 May 2011 12:03:23 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/7192Tip of the Week for Medical Providershttp://rochester.technologypublisher.com/technology/7185Thu, 26 May 2011 12:03:11 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/7185Methods and Systems for Vertigo Treatmenthttp://rochester.technologypublisher.com/technology/6993Fri, 15 Apr 2011 07:01:36 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/6993Data Forms for: Cellular and Molecular Pathophysiology (CAMP) of Facioscapulohumeral Muscular Dystrophy (FSHD) Studyhttp://rochester.technologypublisher.com/technology/6992Fri, 15 Apr 2011 07:01:35 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/6992The Procedure Load Index (PLI)http://rochester.technologypublisher.com/technology/6493Mon, 28 Feb 2011 08:34:35 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/6493Measuring the Ocular Point Spread Function Using Adaptive Opticshttp://rochester.technologypublisher.com/technology/6492Mon, 28 Feb 2011 08:34:29 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/6492Scanning Optical System for a Large Axial Scan Depth Anterior Segment Optical Coherence Tomography (OCT)http://rochester.technologypublisher.com/technology/6491Mon, 28 Feb 2011 08:34:29 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/6491Interferometer on a Chiphttp://rochester.technologypublisher.com/technology/6443Mon, 14 Feb 2011 11:28:18 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/6443The Use of Rad51 Promoter Constructs in Anticancer Therapyhttp://rochester.technologypublisher.com/technology/5917Fri, 29 Oct 2010 11:28:47 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/5917Optical Pulse-Train Generatorhttp://rochester.technologypublisher.com/technology/5874Mon, 18 Oct 2010 10:51:44 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/5874Coded Aperture Optical Imaginghttp://rochester.technologypublisher.com/technology/5865Mon, 18 Oct 2010 10:51:17 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/5865A Multidimensional Real-Time Pain Monitoring Systemhttp://rochester.technologypublisher.com/technology/5863Mon, 18 Oct 2010 10:50:54 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/5863Ceramic Fuel Cell Membrane Containing Aligned Ion-Conducting Pathwayshttp://rochester.technologypublisher.com/technology/5861Mon, 18 Oct 2010 10:50:49 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/5861New Class of Antifungal Agentshttp://rochester.technologypublisher.com/technology/5638Mon, 20 Sep 2010 06:52:02 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/5638Adaptive Optics Scanning Laser Ophthalmoscopehttp://rochester.technologypublisher.com/technology/5580Fri, 27 Aug 2010 10:19:24 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/5580R26STOPrtTA Mouse Strain- a Unique System for Spatiotemporal and Lineage-specific Gene Expressionhttp://rochester.technologypublisher.com/technology/5571Mon, 23 Aug 2010 12:49:07 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/5571HUMMR Antibodyhttp://rochester.technologypublisher.com/technology/5569Mon, 23 Aug 2010 12:49:01 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/5569Dual-Detection of Phase for Full Range Doppler OCThttp://rochester.technologypublisher.com/technology/5111Tue, 04 May 2010 13:47:13 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/5111microEZMix -- A Prefilled Mix and Inject Syringe Systemhttp://rochester.technologypublisher.com/technology/5110Tue, 04 May 2010 13:47:08 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/5110New Recombinant Activated Protein Chttp://rochester.technologypublisher.com/technology/5104Tue, 04 May 2010 13:46:45 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/5104Magnetorheological Finishing Fluid with Zirconia-Coated Carbonyl Iron for Optics Fabricationhttp://rochester.technologypublisher.com/technology/3540Fri, 23 Oct 2009 11:31:46 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/3540Polyclonal anti-GPR56 Antibody Recognizes GPR56 on Formalin-Fixed Paraffin-Embedded Human Tissue Sectionshttp://rochester.technologypublisher.com/technology/3512Thu, 15 Oct 2009 12:06:14 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/3512Novel Transcutaneous Energy Transfer (TET) Devicehttp://rochester.technologypublisher.com/technology/3511Applications: A ventricular assist device (VAD) is an auxiliary blood circulation pump. It is implanted to assist the left, right or both ventricles to enhance circulation. The power source is worn externally by the patient with a cable going through the skin. The opening in the skin becomes a portal for serious infection which may also travel to the heart. Numerous attempts have been made over the years to power VADs transcutaneously. Almost all such attempts have been of some variation of electromagnetic energy transfer from a sending coil outside the body to a receiving coil inside...Thu, 15 Oct 2009 12:06:09 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/3511Monoclonal Antibodies to Dengue Fever NS1http://rochester.technologypublisher.com/technology/3040Wed, 17 Jun 2009 12:03:04 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/3040Monoclonal Antibodies to Dengue Fever E Proteinhttp://rochester.technologypublisher.com/technology/3039Wed, 17 Jun 2009 12:03:03 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/3039Carbazole-Based Host Polymer for Electro-Phosphorescent OLEDshttp://rochester.technologypublisher.com/technology/3037Wed, 17 Jun 2009 12:03:00 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/3037Software for Adaptive Optics: TsunamiSLOhttp://rochester.technologypublisher.com/technology/3028 Brief Description: The software provides user-friendly control of devices needed for adaptive optics: wavefront sensor (Shack-Hartmann or other) with a digital camera, wavefront corrector (such as Boston Micromachines deformable mirror, or ImagineEyes deformable mirror), laser controller (such as Thorlabs ITC-502 or other) and power meters (such as Newport 1930 or other). Applications: For the control of wavefront sensors and aberration correction devices used in adaptive optics in scanning laser ophthalmoscopes, optical coherence tomography and other research applications of adapti...Wed, 17 Jun 2009 12:02:45 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/3028Cholesteric Glassy Liquid Crystals for Selective Wavelength Reflection and Circular Polarizationhttp://rochester.technologypublisher.com/technology/3027Wed, 17 Jun 2009 12:02:43 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/3027High Capacity Embedding in Printed Images by Halftone Orientation Modulationhttp://rochester.technologypublisher.com/technology/3023Wed, 17 Jun 2009 12:02:38 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/3023Software for Computing Zernike Characterization of an Optical Wave Front: TsunamiWavehttp://rochester.technologypublisher.com/technology/3021Wed, 17 Jun 2009 12:02:36 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/3021Flexible, Decoupled Hardware-Accelerated Transactional Memoryhttp://rochester.technologypublisher.com/technology/3016Wed, 17 Jun 2009 12:02:30 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/3016High Sensitivity Interferometers Using Slow- and Fast-Lighthttp://rochester.technologypublisher.com/technology/3014Wed, 17 Jun 2009 12:02:28 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/3014Optical Flip-Flop Latching Switch with Remote Optical Controlhttp://rochester.technologypublisher.com/technology/3013Wed, 17 Jun 2009 12:02:27 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/3013Color Look-Up Tables with Lossless Compressionhttp://rochester.technologypublisher.com/technology/3012Wed, 17 Jun 2009 12:02:26 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/3012Structured Illumination Imaging for in-vitro Microscopy and in-vivo Retinal Imaginghttp://rochester.technologypublisher.com/technology/3008 Brief Description: In structured illumination microscopy, an object is illuminated by sinusoidally patterned light, rather than conventional uniform illumination, and digital image processing is done to obtain axial sectioning (3D imaging) and super-resolution (imaging at frequencies beyond the normal diffraction cutoff of the optical system). Applications: The technique can be used in microscopes for imaging both fluorescent and non-fluorescent objects, such as tissues, cells and micro-structures such as semiconductor chips, in both in vitro and in vivo applications. A key in vivo a...Wed, 17 Jun 2009 12:02:23 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/3008Space-Charge-Free PN Junctionhttp://rochester.technologypublisher.com/technology/3006Wed, 17 Jun 2009 12:02:21 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/3006Measurement of Optical Pulses with Enhanced Dynamic-Range and Increased Bandwithhttp://rochester.technologypublisher.com/technology/3005Wed, 17 Jun 2009 12:02:18 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/3005Double-Focus Imaging Systemhttp://rochester.technologypublisher.com/technology/3003Wed, 17 Jun 2009 12:02:17 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/3003Frequency-Modulated Bistable Display Using Electrowetting and Liquid Dielectrophoresishttp://rochester.technologypublisher.com/technology/3001Wed, 17 Jun 2009 12:02:15 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/3001Ultrasound Imaging of Tissue Stiffness by Spatially Modulated Acoustic Radiation Force Impulse (SM-ARFI)http://rochester.technologypublisher.com/technology/2999Wed, 17 Jun 2009 12:02:13 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2999Efficient Algorithm for Simulating On-Chip RLC Interconnectshttp://rochester.technologypublisher.com/technology/2998Wed, 17 Jun 2009 12:02:12 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2998Distributed Arbitrary Waveform Generatorhttp://rochester.technologypublisher.com/technology/2997Wed, 17 Jun 2009 12:02:10 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2997Method for Nano-Structuring Metal Surfaces by Femto-Second Laser Machininghttp://rochester.technologypublisher.com/technology/2996Wed, 17 Jun 2009 12:02:09 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2996Fluid Management System and Method for Fluid Dispensing and Coatinghttp://rochester.technologypublisher.com/technology/2995Wed, 17 Jun 2009 12:02:08 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2995Ballistic Deflection Transistor and Ballistic Deflection Transistor Based Logic Circuitshttp://rochester.technologypublisher.com/technology/2994Wed, 17 Jun 2009 12:02:08 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2994Enhanced Music and Audio Via Embedded Data in MP3 Fileshttp://rochester.technologypublisher.com/technology/2993Wed, 17 Jun 2009 12:02:07 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2993Behavior-Oriented Parallelization for Multi-Processor Computershttp://rochester.technologypublisher.com/technology/2992Wed, 17 Jun 2009 12:02:06 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2992PC-Compatible Software for X-ray Spectroscopy with an SXX-100http://rochester.technologypublisher.com/technology/2991Wed, 17 Jun 2009 12:02:05 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2991Image sensor with a Current Sensing Active Pixel (CSAP)http://rochester.technologypublisher.com/technology/2989Wed, 17 Jun 2009 12:02:03 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2989Retinal Imaging of Low Light Signalshttp://rochester.technologypublisher.com/technology/2988Wed, 17 Jun 2009 12:02:02 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2988Digital MEMs Amplitude and Phase Control of an Optical Wavefronthttp://rochester.technologypublisher.com/technology/2987Wed, 17 Jun 2009 12:01:59 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2987Hardware-Accelerated Transactional Memoryhttp://rochester.technologypublisher.com/technology/2984Wed, 17 Jun 2009 12:01:53 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2984Image Sensor with a Sigma-Delta ADC Using Only 3 and 4 Transistors/Pixelhttp://rochester.technologypublisher.com/technology/2983Wed, 17 Jun 2009 12:01:53 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2983Distributed Amplifiers with Built-In Filtering for UWB Impulse Radiohttp://rochester.technologypublisher.com/technology/2981Wed, 17 Jun 2009 12:01:51 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2981Blue-Noise Modulated Sigma-Delta Analog-To-Digital Converterhttp://rochester.technologypublisher.com/technology/2980Wed, 17 Jun 2009 12:01:49 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2980Reflective Optical Biosensorhttp://rochester.technologypublisher.com/technology/2977Wed, 17 Jun 2009 12:01:45 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2977Nano-Particle Size Detection by Interferometryhttp://rochester.technologypublisher.com/technology/2975Wed, 17 Jun 2009 12:01:43 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2975Method and Apparatus to Reduce Noise Fluctuations in On-Chip Power Distribution Networkshttp://rochester.technologypublisher.com/technology/2973Wed, 17 Jun 2009 12:01:41 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2973Electrically Addressed Doped Polymer Cholesteric Liquid Crystal Flakes for Optical Device Applicationshttp://rochester.technologypublisher.com/technology/2970Applications: This invention relates to optical devices in which doped PCLC flakes can be used in a host fluid in either passive or active devices with optical properties that can be manipulated and controlled by an electric field for use in information displays, shutters, switchable filters, polarizers, wavelength selective mirrors, etc. Advantages: This invention uses micron sized PCLC flakes doped with a variety of materials such as titanium dioxide, barium titanate, carbon black, metal particles, etc. suspended in a host fluid system to manipulate the angular motion of the flakes in resp...Wed, 17 Jun 2009 12:01:36 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2970Retinal Imaging with Adaptive Optics Optical Coherence Tomography (AO-OCT)http://rochester.technologypublisher.com/technology/2967Wed, 17 Jun 2009 12:01:32 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2967Genetic Engineered Clostridium Thermocellum for Ethanol Production from Cellulosehttp://rochester.technologypublisher.com/technology/2966Wed, 17 Jun 2009 12:01:30 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2966Ultrasound Distortion Compensation Using a “Blind System Identification” Methodhttp://rochester.technologypublisher.com/technology/2963Wed, 17 Jun 2009 12:01:28 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2963Multi-Frequency Open-Channel DEP Cell Sorting Integrated with DEP Microfluidic Systemhttp://rochester.technologypublisher.com/technology/2961Wed, 17 Jun 2009 12:01:26 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2961Reconstruction of an Image Mosaichttp://rochester.technologypublisher.com/technology/2960Wed, 17 Jun 2009 12:01:25 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2960An Input Signal Power Sensing Sentry for Smart-Sensor Applicationshttp://rochester.technologypublisher.com/technology/2958Wed, 17 Jun 2009 12:01:22 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2958Change Detection and Object Discovery in Videohttp://rochester.technologypublisher.com/technology/2957Wed, 17 Jun 2009 12:01:21 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2957Fiber Laser Dispersion Compensatorhttp://rochester.technologypublisher.com/technology/2956Wed, 17 Jun 2009 12:01:20 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2956Image Sensor with a Sigma-Delta ADC at Every Pixelhttp://rochester.technologypublisher.com/technology/2953Wed, 17 Jun 2009 12:01:16 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2953Image Authentification and Data Embeddinghttp://rochester.technologypublisher.com/technology/2952Wed, 17 Jun 2009 12:01:15 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2952High Gain Bulk-Driven Operational Amplifiers for SOC Applicationshttp://rochester.technologypublisher.com/technology/2951Wed, 17 Jun 2009 12:01:14 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2951Metrics to Predict the Subjective Impact of the Eye's Wave Aberrationhttp://rochester.technologypublisher.com/technology/2950Wed, 17 Jun 2009 12:01:12 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2950Magnetic Nano-Particles, Nanocomposites, and Filmshttp://rochester.technologypublisher.com/technology/2948Wed, 17 Jun 2009 12:01:10 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2948OLED Materials for Polarized, Tunable Color (and White) Emissionhttp://rochester.technologypublisher.com/technology/2947Wed, 17 Jun 2009 12:01:08 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2947Glassy Liquid Crystals (GLCs) for Optical Polarizing Filmshttp://rochester.technologypublisher.com/technology/2945Wed, 17 Jun 2009 12:01:06 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2945Wireless Control Protocol for Energy Efficiency in Ad-Hoc Networkshttp://rochester.technologypublisher.com/technology/2944Wed, 17 Jun 2009 12:01:05 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2944Switched-Capacitor Filter for the Mirrored Integrator ADChttp://rochester.technologypublisher.com/technology/2942Wed, 17 Jun 2009 12:01:03 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2942Wireless Control Protocol for Energy Efficiencyhttp://rochester.technologypublisher.com/technology/2940Wed, 17 Jun 2009 12:01:01 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2940Temporal Affinity Analysis Optimization for Software Performancehttp://rochester.technologypublisher.com/technology/2938Wed, 17 Jun 2009 12:00:59 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2938A Metric for Computing Subjective Sharpness From Wave Sensor Datahttp://rochester.technologypublisher.com/technology/2936Wed, 17 Jun 2009 12:00:55 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2936Domino Logic with Variable Threshold Voltage Keeperhttp://rochester.technologypublisher.com/technology/2935The invention offers a high speed, low power domino logic circuit for microprocessors. The design involves a dynamic body biased keeper circuit which simultaneously reduces power consumption and enhances speed.. Applications For CMOS logic circuits requiring high speed. Advantages Domino CMOS logic circuits which are commonly used in high performance microprocessors for their high speed and area characteristics, are highly sensitive to noise as compared to static gates. In standard domino logic gates, a feedback keeper is employed to maintain the state of the dynamic node against coupling n...Wed, 17 Jun 2009 12:00:54 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2935Monodisperse Conjugated Oligomers for Polarized Light Emissionhttp://rochester.technologypublisher.com/technology/2930Wed, 17 Jun 2009 12:00:47 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2930Side-Coupled Integrated Spaced Sequence of Resonators (SCISSOR)http://rochester.technologypublisher.com/technology/2929Wed, 17 Jun 2009 12:00:46 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2929Sigma-Delta Analog to Digital Converter Architecture Based upon a Novel Modulator Design Employing a Mirrored Integratorhttp://rochester.technologypublisher.com/technology/2926Wed, 17 Jun 2009 12:00:42 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2926Adaptive Issue Queue for Reduced Power at High Performancehttp://rochester.technologypublisher.com/technology/2925Wed, 17 Jun 2009 12:00:41 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2925Manufacture of High Temperature Materials by Combustion Synthesis and Semi-Solid Forminghttp://rochester.technologypublisher.com/technology/2918Wed, 17 Jun 2009 12:00:33 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2918An Objective Method to Determine the Ocular Refraction from Wavefront Aberration Data and to Design an Optimum Customized Correction of a Set of a Few Higher-Order Aberrationshttp://rochester.technologypublisher.com/technology/2915Wed, 17 Jun 2009 12:00:29 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2915Super-Conducting Single Photon Detectorhttp://rochester.technologypublisher.com/technology/2913Wed, 17 Jun 2009 12:00:26 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2913All Optical Flip Flop Using a Resonant-Type Semiconductor Optical Amplifierhttp://rochester.technologypublisher.com/technology/2909Wed, 17 Jun 2009 12:00:22 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2909Culturing Leukemia Cells in a Bio-Reactor for Drug Discovery and Diagnosishttp://rochester.technologypublisher.com/technology/2907Wed, 17 Jun 2009 12:00:20 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2907Rapid, Automatic Measurement of the Eye's Wave Aberrationhttp://rochester.technologypublisher.com/technology/2906Wed, 17 Jun 2009 12:00:18 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2906Ultra-Short Optical Pulse Measurement Using a Spectral Shearing Interferometerhttp://rochester.technologypublisher.com/technology/2893Wed, 17 Jun 2009 12:00:04 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2893Glassy Chiral Nematic Polymershttp://rochester.technologypublisher.com/technology/2885This material is a glassy thermotropic chiral nematic liquid crystalline composition with low molar mass, which is used for forming optical devices with clear transparent films that selectively reflect visible and near-infrared circular-polarized light, but do not absorb light in the visible region. Applications This material can be used in circular polarizing filters, selective reflectors, beam splitters, beam apodizers or notch filters. Advantages Currently, low molecular weight liquid crystal materials have many limitations including durability, effective temperature, mesophase stability,...Wed, 17 Jun 2009 11:59:54 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2885Improving Vision and the Resolution of Retinal Images by Measuring and Correcting the Wave Aberration of the Eyehttp://rochester.technologypublisher.com/technology/2876Wed, 17 Jun 2009 11:59:41 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2876Mice Carrying Null or Conditional Mutations in the Bambi Genehttp://rochester.technologypublisher.com/technology/2874Wed, 17 Jun 2009 11:59:37 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2874A Behavior Observational Instrumenthttp://rochester.technologypublisher.com/technology/2873Wed, 17 Jun 2009 11:59:36 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2873Med Schedule - A Web-based Software Solution for Nursing Staff Schedule Managementhttp://rochester.technologypublisher.com/technology/2871Wed, 17 Jun 2009 11:59:33 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2871The Ontology Mapperhttp://rochester.technologypublisher.com/technology/2870Wed, 17 Jun 2009 11:59:30 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2870Needle Shadehttp://rochester.technologypublisher.com/technology/2863Wed, 17 Jun 2009 11:59:05 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2863Compounds Enhancing Platelet Productionhttp://rochester.technologypublisher.com/technology/2861 Applications: The invention identifies novel compounds that enhance platelet production in cases where platelet number is low, such as after ionizing radiation exposure, chemotherapy, and autoimmunity. Advantages: Existing therapy such as TPO (thrombopoietin) only enhances production of megakaryocytes but does not directly enhance the production of platelets.Wed, 17 Jun 2009 11:59:02 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2861Recombinant Plasminogen Activator Inhibitor-1 (PAI-1) for the Treatment or Prevention of Acute Lung Injury and Death in Severe Pulmonary Infectionhttp://rochester.technologypublisher.com/technology/2858Wed, 17 Jun 2009 11:58:44 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2858Human KC-NL Crosstalk Subversion by HCVhttp://rochester.technologypublisher.com/technology/2857Wed, 17 Jun 2009 11:58:42 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2857Protein Kinase C-Associated Kinase PKK is Required for NF-kB Signaling and Survival in Diffuse Large-B Cell Lymphoma Cellshttp://rochester.technologypublisher.com/technology/2855Wed, 17 Jun 2009 11:58:38 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2855Identification of a Novel Stem Cell Markerhttp://rochester.technologypublisher.com/technology/2854 Applications: The invention identifies a Novel Stem Cell Marker Gpr177, a G Protein-coupled Receptor. Gpr177 is a useful marker in the identification, isolation and characterization of specific stem cell population, including neural stem cells in specific regions of the brain and spinal cord, and cancer stem cells as well. Advantages: The Gpr177-expressing stem cells have potential for the treatment of the brain and spinal cord injuries, the neuromuscular malfunction, and the learning and memory disorders. Because Gpr177 presents in unglycosylated and glycosylated forms, it is also ...Wed, 17 Jun 2009 11:58:37 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2854Mouse Model of Chronic Viral Hepatitishttp://rochester.technologypublisher.com/technology/2853 Applications: The invention generates a novel mouse model of acute and chronic T cell mediated hepatitis, which shares some important features with viral hepatitis in man. The mouse model is valuable in identifying drug targets for viral hepatitis. Advantages: The mouse model is driven directly by CD8+ T cell and results from the recognition of an antigen that is expressed in a minority of hepatocytes. The mouse model does not depend on transgenic expression of the antigen and is not complicated by immune self-tolerance. The model results in the induction of genes associated with li...Wed, 17 Jun 2009 11:58:36 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2853Novel Intra-Ocular Pressure Regulating Devicehttp://rochester.technologypublisher.com/technology/2850Wed, 17 Jun 2009 11:58:30 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2850A Training Curriculum for Mental Health and Spiritual Care Professionals in Healthcare Settingshttp://rochester.technologypublisher.com/technology/2849This is a set of disaster behavioral health training materials for health and non-healthcare workers (Tech IDs: 6-1583-86). Applications The materials will be used to train behavioral health, spiritual care and other community helpers to respond to the needs of individuals impacted by disasters and public health emergencies. It can be utilized by state and local health and mental health agencies and other disaster response organizations to train their personnel. The curriculum titled ?Disaster Mental Health: A Critical Response? is composed of the following:. Instructor Edition (6-1583). Inst...Wed, 17 Jun 2009 11:58:26 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2849A Training Curriculum for Mental Health and Spiritual Care Professionals in Healthcare Settingshttp://rochester.technologypublisher.com/technology/2848 This is a set of disaster behavioral health training materials for health and non-healthcare workers (Tech IDs: 6-1583-86). Applications The materials will be used to train behavioral health, spiritual care and other community helpers to respond to the needs of individuals impacted by disasters and public health emergencies. It can be utilized by state and local health and mental health agencies and other disaster response organizations to train their personnel. The curriculum titled ?Disaster Mental Health: A Critical Response? is composed of the following:. Instructor Edition (6-1583). Ins...Wed, 17 Jun 2009 11:58:24 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2848A Training Curriculum for Mental Health and Spiritual Care Professionals in Healthcare Settingshttp://rochester.technologypublisher.com/technology/2847 This is a set of disaster behavioral health training materials for health and non-healthcare workers (Tech IDs: 6-1583-86). Applications The materials will be used to train behavioral health, spiritual care and other community helpers to respond to the needs of individuals impacted by disasters and public health emergencies. It can be utilized by state and local health and mental health agencies and other disaster response organizations to train their personnel. The curriculum titled ?Disaster Mental Health: A Critical Response? is composed of the following:. Instructor Edition (6-1583). Ins...Wed, 17 Jun 2009 11:58:23 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2847A Training Curriculum for Mental Health and Spiritual Care Professionals in Healthcare Settingshttp://rochester.technologypublisher.com/technology/2846Wed, 17 Jun 2009 11:58:22 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2846Carbohydrate-targeted Therapeutic Agents, Diagnostics, and Sensorshttp://rochester.technologypublisher.com/technology/2841 Applications: Carbohydrates represent a particularly enticing and important challenge to the organic chemist interested in molecular recognition. In addition to their role in addressing the fundamental problem of understanding binding and selectivity, novel carbohydrate receptors have significant potential as tools in the rapidly evolving field of glycomics, as components of sensing systems for isolated sugar and for pathogens, and as leads for the development of new therapeutic agents. The invention identifies a small molecule that binds carbohydrates with high affinity via non-covale...Wed, 17 Jun 2009 11:58:04 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2841Modulating Melanin Expressionhttp://rochester.technologypublisher.com/technology/2839Wed, 17 Jun 2009 11:57:59 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2839RNA-Targeted Small Molecules as Potential Antiviral Therapy (HIV, SARS etc)http://rochester.technologypublisher.com/technology/2838Wed, 17 Jun 2009 11:57:57 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2838Antigen Release Beads for a Quantitative ELISPOT or FLORISPOT Assayhttp://rochester.technologypublisher.com/technology/2834 Applications: This research has developed a method to quantify the specific amount of antigen released by cells in an ELISPOT assay. Advantages: Currently, an ELISPOT assay can only quantify the number of cells producing a particular antigen. This technology allows the user to create a standard curve for antigen release and determine the actual amount of antigen released by the cells.Wed, 17 Jun 2009 11:57:48 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2834<![CDATA[Reagents Identifying PPARγ Isoforms]]>http://rochester.technologypublisher.com/technology/2832Applications: Reagents can be used for commercial western blot/ELISA/Flow Cytometry. Advantages: Currently there are no proven reagents that distinguish PPAR gamma isoforms.Wed, 17 Jun 2009 11:57:37 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2832Provider Portal/Web Bed Boardhttp://rochester.technologypublisher.com/technology/2828Wed, 17 Jun 2009 11:57:24 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2828Polyketal Nanoparticles (PKNs): a Novel Macrophage-Selective Drug-Delivery Systemhttp://rochester.technologypublisher.com/technology/2827Wed, 17 Jun 2009 11:57:23 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2827Kcnn4 Knockout Mousehttp://rochester.technologypublisher.com/technology/2825 Applications: The Kcnn4 Knockout Mouse model will be helpful for developing treatment for sickle cell anemia and diarrhea. Advantages: Kcnn4 Knockout Mouse model can be used for testing function, related genetic diseases and treatment related to the Kcnn4 gene.Wed, 17 Jun 2009 11:57:19 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2825Human Biliverdin Reductase is a New Member of the Insulin Receptor Substrate Family with Serine/Threonine/Tyrosine Kinase Activityhttp://rochester.technologypublisher.com/technology/2823Wed, 17 Jun 2009 11:57:15 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2823Pediatric Blood Pressure Screening Wheelhttp://rochester.technologypublisher.com/technology/2820Wed, 17 Jun 2009 11:57:06 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2820A Model to Study the Role of IL-1ß in Neurodegeneration and Brain Injuryhttp://rochester.technologypublisher.com/technology/2819 Applications: A novel transgenic mouse model was created to investigate the role of IL1ß in neurodegeration and brain injury. This model may also be used to test existing and novel drugs and therapies for suppression of neuroinflammation associated with brain disorders. Advantages: Creation of conditionally expressed IL1ß and IL-1A (receptor antagonist) mice provides an important tool for dissection of the role of IL-1 in brain and newrodegeration.Wed, 17 Jun 2009 11:57:05 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2819Mouse Model of Osteoarthritis: Over-Expression of Smurf2 in Cartilage to Induce Disease and Over-expression of Smurf1 as a Potential Therapeutic Strategyhttp://rochester.technologypublisher.com/technology/2815Wed, 17 Jun 2009 11:56:54 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2815Recombinant GST-Tagged Vitronectin Can Be Used as a Cell-Culture Substratumhttp://rochester.technologypublisher.com/technology/2814Wed, 17 Jun 2009 11:56:52 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2814DNA Cell Lines for the Study of Long QT Syndromehttp://rochester.technologypublisher.com/technology/2813Applications: As part of a study on Long QT syndrome, these cell lines were obtained from approximately 600 affected and unaffected individuals are available for license in other fields of cardiac research.Wed, 17 Jun 2009 11:56:49 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2813Quaternary Antimuscarinic Compounds for the Treatment of Bladder Diseaseshttp://rochester.technologypublisher.com/technology/2807Wed, 17 Jun 2009 11:56:24 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2807Compounds for Use in Cocaine Abuse with Reduced Opoid Side Effectshttp://rochester.technologypublisher.com/technology/2802Wed, 17 Jun 2009 11:56:08 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2802Monoclonal Antibodies to Yellow Fever E Proteinhttp://rochester.technologypublisher.com/technology/2801Wed, 17 Jun 2009 11:56:02 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2801Expression of Enhanced Green Fluorescence Protein in Pulmonary Type II Epithelial Cells of Micehttp://rochester.technologypublisher.com/technology/2798Wed, 17 Jun 2009 11:55:57 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2798Novel Autoinducer Molecules and Uses Therefore (Quinoline Signaling in the Cell-to-Cell Communication)http://rochester.technologypublisher.com/technology/2797Wed, 17 Jun 2009 11:55:55 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2797Use of Molecular Techniques to Identify Regulators of Bone Formationhttp://rochester.technologypublisher.com/technology/2796Wed, 17 Jun 2009 11:55:54 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2796Transgenic Mouse Model of Parkinson's Disease Containing Either Wild-Type or Doubly-Mutated Human Alpha-synucleinhttp://rochester.technologypublisher.com/technology/2794Wed, 17 Jun 2009 11:55:50 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2794HSA LR Mice (Mouse Model of Myotonic Dystrophy)http://rochester.technologypublisher.com/technology/2793Wed, 17 Jun 2009 11:55:49 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2793A Mouse Line that Lacks Phosphoinositidehttp://rochester.technologypublisher.com/technology/2791Wed, 17 Jun 2009 11:55:46 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2791Database for CARE-HD Trial Sponsored by NINDShttp://rochester.technologypublisher.com/technology/2790 Applications: The database provides information on whether remacemide and/or coenzyme Q can effectively treat Huntington's disease. Advantages: The database is a unique collection of data from 30 months of clinical trials. Technology Status: The database is ready for use.Wed, 17 Jun 2009 11:55:43 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2790Dioxin Responsive lacZ Mouse Modelhttp://rochester.technologypublisher.com/technology/2789 Applications: The mouse model provides a useful tool for both the examination of the endogenous role of the Ah receptor in proliferation or differentiation and of the developmental targets of dioxin-like compounds. Advantages: A useful model for studying how dioxin-like compounds affects Ah receptors in vivo.Wed, 17 Jun 2009 11:55:36 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2789A Cell Line Capable of Sensing HIF-1alpha Activation in the CNS for Use in Screening Pharmacologic Agents Capable of Activating/Attenuating Hypoxic Activated Gene Transcriptionhttp://rochester.technologypublisher.com/technology/2787Applications: This technology describes a stable reporter cell line that measures the expression of hypoxia-inducible-1-alpha (HIF-1a), a transcriptional activator, which is useful in screening compound libraries for anti-ischemic, neuroprotective and tumor pro-apoptotic activity. Drug candidates identified with this technology could potentially address therapies for central nervous system ischemia, cardiac ischemia, and cancer. Advantages: This cell lines offer a fast and economical tool to learn how drug leads can regulate pathologic hypoxia-dependent transcriptional processes such ...Wed, 17 Jun 2009 11:55:33 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2787Reactivity/Selectivity Methods For Calibrating Predictive Models for P450http://rochester.technologypublisher.com/technology/2786Wed, 17 Jun 2009 11:55:31 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2786Animal Model for the Testing of Allergens and Irritantshttp://rochester.technologypublisher.com/technology/2783Wed, 17 Jun 2009 11:55:26 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2783Transgenic Mice Expressing Human PSAhttp://rochester.technologypublisher.com/technology/2779Wed, 17 Jun 2009 11:55:18 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2779E1-A Immortalized Retinal (E1A-NR.3) Cell Culturehttp://rochester.technologypublisher.com/technology/2778 Applications The established retinal cell line retains retinal properties, is non-tumorigenic but immortal. It is ideal for in-vitro drug screening. Advantages It is one of very few retinal cell lines. Technology Status E1 cell line is ready for use.Wed, 17 Jun 2009 11:55:17 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2778<![CDATA[Hybridoma Cell Line & Monoclonal Antibodies Named IV.3]]>http://rochester.technologypublisher.com/technology/2775Wed, 17 Jun 2009 11:55:08 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2775Circulating Osteoclast Precursors as Markers of Bone Resorption in Inflammatory Arthritishttp://rochester.technologypublisher.com/technology/2281Tue, 05 May 2009 12:22:03 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2281Acoustically Induced Blood Stasis and in vivo Optical Spectroscopy Thereofhttp://rochester.technologypublisher.com/technology/2273Tue, 05 May 2009 11:30:01 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2273Monoclonal Antibodies to von Willebrand Factor Propolypeptide (VWFpp)http://rochester.technologypublisher.com/technology/2272Tue, 05 May 2009 11:30:01 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2272Non-Invasive in-vivo Imaging of Mechanoreceptors in Human Skin Using Confocal Microscopyhttp://rochester.technologypublisher.com/technology/2271Tue, 05 May 2009 11:30:00 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2271Novel Human Papillomavirus (HPV) Chimeric Virus Like Particle (cVLP)-Based Gene Delivery System for Phrophylaxis and Immunotherapy of Infectious Diseaseshttp://rochester.technologypublisher.com/technology/2248Mon, 04 May 2009 14:19:36 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2248Stabilized Outersurface Protein A Fragment as a Lyme Disease Vaccinehttp://rochester.technologypublisher.com/technology/2244Mon, 04 May 2009 14:19:32 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2244Transcutaneous Immunization Against Papillomavirus Diseasehttp://rochester.technologypublisher.com/technology/2243Brief Description: This invention is a method of vaccinating against human papillomavirus (HPV) by using papillomavirus ?virus-like particles? transcutaneously to induce an immune response to the virus. Applications: Papiloma viruses constitute a group of DNA viruses that induce both lytic infections and either benign or malignant tumors. Papiloma viruses infect cutaneous, genital, oral, and respiratory epithelia in a tissue-specific manner. Infection with HPV has been associated closely with plantar warts, condylomata acuminata (anogenital warts), and premalignant and malignant lesio...Mon, 04 May 2009 14:19:31 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2243Stable Human Fc Receptor-Transformed Cell Lines to Detect Virus-Neutralizing and Enhancing Antibodieshttp://rochester.technologypublisher.com/technology/2235Mon, 04 May 2009 08:54:55 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2235Detection and Treatment of Interstitial Cystitishttp://rochester.technologypublisher.com/technology/2132Fri, 17 Apr 2009 13:12:06 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2132RECRUIT - A Database Solution for the Management of Clinical Trial Recruitmenthttp://rochester.technologypublisher.com/technology/2131Fri, 17 Apr 2009 12:54:36 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2131MADDIT II Blood Sampleshttp://rochester.technologypublisher.com/technology/2126Fri, 17 Apr 2009 11:52:23 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2126Small molecules Manipulation of G Protein Subunit Signaling for Chronic Pain Management and Opioid-Tolerancehttp://rochester.technologypublisher.com/technology/2125Fri, 17 Apr 2009 11:45:51 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2125Predicting the Risk for Recurrent Heart Attack(s)http://rochester.technologypublisher.com/technology/2124Fri, 17 Apr 2009 11:19:36 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2124A Novel Approach to Treating Multiple Diseases by Small Molecule Targeting of G-Proteins - One Step Beyond GPCRshttp://rochester.technologypublisher.com/technology/2119Fri, 17 Apr 2009 09:13:11 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2119Inhibition of Molecular Mediators in TNF-Signaling (Inflammation) for the Treatment of Cardiovascular Diseases Such as Atherosclerosis, Stroke, and Ischemia/Reperfusion Injuryhttp://rochester.technologypublisher.com/technology/2118Fri, 17 Apr 2009 08:59:25 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2118Tissue Factor Pathway Inhibition as a Treatment Strategy for Severe Pulmonary Arterial Hypertensionhttp://rochester.technologypublisher.com/technology/2102Wed, 15 Apr 2009 13:47:11 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2102Optimized Cell Preparations for Allogeneic Repair of Injured Human White Matterhttp://rochester.technologypublisher.com/technology/2064Mon, 13 Apr 2009 12:08:29 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2064Human-Mouse Chimeric Model to Assess in vivo Response of Human Glial to Injury, Disease Perturbation, and Drug Treatmenthttp://rochester.technologypublisher.com/technology/2062 Applications: The invention has generated chimeric human-mouse brains in which the relative proportion of human astrocytes and oligodendrocytes is quite high, often exceeding 50% of all cells in the adult white matter. More over, researchers have established mice in which 100% of myelin, in substantially normal myelinated brain, is of human origin. Advantages: In vivo responses of human glia -including glial progenitor cells, astrocytes, and oligodendrocytes- to injury and disease states may be imaged and biochemically assessed, in a mouse model that permits disease perturbation, drug treatm...Mon, 13 Apr 2009 08:33:16 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2062Mouse Model of Osteoarthritishttp://rochester.technologypublisher.com/technology/2014Applications: Osteoarthritis (OA) is a common degenerative joint disease and currently there is no effective treatment for the diseases. We have generated a conditional activation genetic mouse model that can help to identify new drugs for the prevention and treatment of osteoarthritis. The mouse model can also test the effect and efficacy of existing or newly identified osteoarthritis drugs. Advantages: Using the mouse model, we demonstrate for the first time that over expression of a key gene in articular chondrocytes leads to the development of OA in adult mouse.Fri, 10 Apr 2009 09:06:03 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/2014Repair and Regeneration of Articular Cartilage, and the Repair and Regeneration of Fibrocartilaginous Tissueshttp://rochester.technologypublisher.com/technology/1926Mon, 06 Apr 2009 13:03:49 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/1926Freeze-Dried Tendon Allografts as Delivery Vehicles for Geneshttp://rochester.technologypublisher.com/technology/1921Mon, 06 Apr 2009 13:03:39 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/1921Method to Correct for Skeletal Lead Interference in Bone Mineral Density Measurementshttp://rochester.technologypublisher.com/technology/1920Mon, 06 Apr 2009 13:03:36 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/1920High Affinity Binding Proteins to Integrinshttp://rochester.technologypublisher.com/technology/1885Applications: This technology is related to the development of high affinity binding proteins to specific integrin proteins highly associated with cancer metastasis. Applications of these targeting molecules include tumor imaging, targeted tumor therapy, and targeted gene delivery. Advantages: These molecules are more stable, easier to make, and more amenable to protein engineering techniques than short peptides and antibodies.Mon, 30 Mar 2009 08:35:05 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/1885Robot-Assisted Platform for Intratumoral Delivery (RAPID) Systemhttp://rochester.technologypublisher.com/technology/1881Fri, 27 Mar 2009 13:03:07 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/1881Photodynamic Therapy with Spatially-Resolved Dual Spectroscopic Monitoring and Related Systemhttp://rochester.technologypublisher.com/technology/1811Brief Description: Since 2003, a collaborative research effort between researchers at the University of Rochester Medical Center (URMC) and the Roswell Park Cancer Institute (RPCI) has resulted in the development of a system for delivery of photodynamic therapy(PDT) for the treatment of cancer with capabilities for realtime spectroscopic monitoring and feedback controlled dosimetry. Applications: This invention involves instrumentation developed for delivery of spatially resolved photodynamic therapy(PDT) in vivo, employing real-time measurements of fluorescence emission spectra correc...Tue, 24 Mar 2009 13:18:54 GMTdavid_englert@urmc.rochester.eduhttp://rochester.technologypublisher.com/technology/1811