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Novel Human Papillomavirus (HPV) Chimeric Virus Like Particle (cVLP)-Based Gene Delivery System for Phrophylaxis and Immunotherapy of Infectious Diseases
Applications:As demonstrated in vitro and in vivo results, HPV VLPs, preferably chimeric HPV L1/L2 VLPs, are useful for facilitating delivery and expression of plasmid DNA to antigen presenting cells, and for enhanced induction of immune responses against co-administered plasmid DNA-based immunogens. Results also demonstrate enhanced immune respons...
Published: 5/4/2009   |   Inventor(s): Robert Rose, Christine Malboeuf, Youngeun Ellen Lee Son, Christopher Lane
Keywords(s): Vaccine
Category(s): Vaccines