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Stable Human Fc Receptor-Transformed Cell Lines to Detect Virus-Neutralizing and Enhancing Antibodies

Applications:The invention offers a novel method to screen anti-flavivirus antibodies in blood for neutralizing and replication-enhancing antibodies using Fc gamma R transformed macrophages. Although this invention is immediately applicable to dengue virus infection, in principle it is applicable to any viral pathogen whose replication may be enhanced...

Published: 5/23/2023 | Inventor(s): Jacob Schlesinger, Robert Rose, W.W. Shanaka Rodrigo, Xia Jin

Keywords(s): Vaccine

Category(s): Vaccines