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Septin inhibitors for treatment of cancer
Background Effective therapeutic options are limited for the treatment of liver, lung, renal, ovarian, endometrial and pancreatic cancer. Successive second- and third-line therapies do not add meaningful responses besides adding numerous life-debilitating toxicities. In order to improve the survival rate of patients diagnosed with these lethal malignancies,...
Published: 5/7/2024
|
Inventor(s):
Richard Moore
,
Rakesh Singh
,
Kyu Kwang Kim
,
Rachael Turner
Keywords(s):
Category(s):
Therapeutic
URML-3881, a Novel MEK Inhibitor for the Treatment of Cancers
Provided herein, are compounds, compositions, and methods of treatment of cancers using an inhibitor of MAPK/ERK Kinase (MEK), in particular hydrazine derivatives.
Published: 5/7/2024
|
Inventor(s):
Richard Moore
,
Rakesh Singh
,
Rachael Turner
,
Kyu Kwang Kim
,
Negar Khazan
Keywords(s):
Category(s):
Therapeutic