Search Results - kyu+kwang+kim

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Septin inhibitors for treatment of cancer
Background Effective therapeutic options are limited for the treatment of liver, lung, renal, ovarian, endometrial and pancreatic cancer. Successive second- and third-line therapies do not add meaningful responses besides adding numerous life-debilitating toxicities. In order to improve the survival rate of patients diagnosed with these lethal malignancies,...
Published: 5/7/2024   |   Inventor(s): Richard Moore, Rakesh Singh, Kyu Kwang Kim, Rachael Turner
Keywords(s):  
Category(s): Therapeutic
Small molecule inhibitor of human epididymis protein 4 (HE4) for treating cancer
­Background Epithelial ovarian cancer (EOC), is the fifth leading cause of cancer deaths in women, and the deadliest of all gynecologic cancers. The response of current chemotherapies has plateaued, creating a severe unmet need for superior therapies. Human epididymis protein 4 (HE4) is inordinately overexpressed in over 70% of EOC patients, acts...
Published: 5/7/2024   |   Inventor(s): Richard Moore, Rakesh Singh, Kyu Kwang Kim
Keywords(s):  
Category(s): Therapeutic
URML-3881, a Novel MEK Inhibitor for the Treatment of Cancers
Provided herein, are compounds, compositions, and methods of treatment of cancers using an inhibitor of MAPK/ERK Kinase (MEK), in particular hydrazine derivatives.
Published: 5/7/2024   |   Inventor(s): Richard Moore, Rakesh Singh, Rachael Turner, Kyu Kwang Kim, Negar Khazan
Keywords(s):  
Category(s): Therapeutic