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Protease Activated Cytokines as Anti-Cancer Therapy
A novel therapy method for delivering localized anti-cancer responses without adverse body-wide side effects. Problem Solved by the Technology Despite remarkable success at identifying tumor-associated antigens (TAA), generating effective anti-tumor immune response has not been successful at eliminating tumors. Systemically administered active drugs...
Published: 10/28/2024
|
Inventor(s):
John Frelinger
,
John Puskas
,
Baek Kim
,
Mark Sullivan
Keywords(s):
Cancer
,
Immunotherapy
,
Oncology
,
Therapy
Category(s):
Therapeutic
3' Deoxy Nucleosides and Their Analogs as Anti-HIV Agents Targeting HIV-1 Macrophage Infection
3' Deoxy Nucleosides and Their Analogs as Anti-HIV Agents Targeting HIV-1 Macrophage Infection
Published: 10/28/2024
|
Inventor(s):
Baek Kim
Keywords(s):
Antiviral
,
Drug Design
,
HIV
,
Infectious Disease
Category(s):
Therapeutic
Protein Transducing Domain/Deaminase Chimeric Proteins, Related Compounds, and Uses Thereof
Applications:Along with 1174, the present invention is directed to provide a chimeric protein capable of transduction into B cells for purposes of treating Class Switch Recombination and Somatic Hypermutation, both involved in antibody production and diversity, as well as other conditions such as B cell lymphoma.
Published: 5/7/2024
|
Inventor(s):
Harold Smith
,
Mark Sowden
,
Stephen Dewhurst
,
Baek Kim
,
Joseph Wedekind
Keywords(s):
Cancer
,
Gene Therapy
,
Oncology
Category(s):
Therapeutic
Improved Safer Nasal Spray Flu Vaccines
A novel live attenuated influenza virus nasal vaccine safe enough for use by young children and asthmatics.Problem Solved by this TechnologyYoung children, pregnant women, and persons with compromised immune systems are at high risk for complications arising from an influenza infection. These people are currently served with sub-dermal, or nasal applications...
Published: 10/28/2024
|
Inventor(s):
Stephen Dewhurst
,
Andrew Cox
,
John Treanor
,
Baek Kim
Keywords(s):
Category(s):
Vaccines