Transgenic Mice Expressing Human PSA

Brief Description
Applications
Human prostate-specific antigen (PSA) has been widely used as a serum marker for cancer of the prostate.  The cell type-specific expression of PSA also makes it a potential tumor antigen for prostate cancer immunotherapy.

Advantages
Generation of a mouse model expressing human PSA allows for the study of the immunological aspects of this protein within either normal or malignant prostate tissue.
Patent Information:
Category(s):
Research Tools
For Information, Contact:
Matan Rapoport
Licensing Associate
University of Rochester
585.276.6600
matan.rapoport@rochester.edu
Inventors:
John Frelinger
Chungwen Wei
Richard Barth
Keywords:
Research Tool