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Use of a Heme Tag for Expressed Protein Purification, Visualization, and Quantitation
The heme tag is a heme convalently bound to a peptide appended to a protein of interest. It's used for 1) affinity purification of a protein. 2) Visual tracking of a protein during expression and purification 3) quantization of a protein using absorption spectroscopy 4) determination of a protein?s extinction coefficient at 280nm.Applications:This ...
Published: 4/25/2019   |   Inventor(s): Kara Bren, Wesley Asher
Keywords(s):  
Category(s): Research Tools
The Myotonic Dystrophy Type-1 Health Index (MDHI Type-1) Italian Translation
The Myotonic Dystrophy Health Index (MDHI) Italian Version is a survey designed to efficiently measure the overall level of disease burden in a patient with myotonic dystrophy type-1 whose native language is Italian. This disease-specific patient-reported outcome measure is designed is designed to reliably and responsively measure therapeutic benef...
Published: 4/15/2019   |   Inventor(s): Chad Heatwole
Keywords(s):  
Category(s): Copyright, Informatics, Research Tools
A Functional Monoclonal Antibody Against DC-STAMP
Brief Description: Bone is a very dynamic organ as evidenced by the process of bone remodeling which relies on a delicate balance between bone formation and bone resorption and is orchestrated by osteoblasts (OB) and osteoclasts (OC). The coordinated interplay of OB and OC continuously remodels bone through highly regulated molecular and cellul...
Published: 7/24/2018   |   Inventor(s): Kofi Mensah, Yahui Grace Chiu, Christopher Ritchlin, Edward Schwarz
Keywords(s): Antibody, Anti-inflammatory, Inflammation, Orthopaedics, Osteoporosis, Reagent
Category(s): Research Tools
The Charcot-Marie-Tooth Disease Health Index (CMT-HI)
The CMT-Health Index (CMT-HI) is a disease-specific, patient-reported, outcome measure designed to reliably and responsively measure therapeutic benefit in Charcot-Marie-Tooth disease (CMT) clinical trials. The CMT-HI may also be used to measure overall patient health in a clinical setting. It covers the 18 areas of greatest importance to the adult...
Published: 6/30/2016   |   Inventor(s): Chad Heatwole, David Herrmann, Nicholas Johnson
Keywords(s):  
Category(s): Copyright, Informatics, Research Tools
The Myotonic Dystrophy Health Index Short Form (MDHI-SF)
The Myotonic Dystrophy Health Index Short Form (MDHI-SF) is a brief survey designed to efficiently measure the overall level of disease burden in a patient with myotonic dystrophy type-1. It covers the 17 areas of greatest importance to the adult myotonic dystrophy population. This instrument was developed and validated through the outcome measures...
Published: 6/30/2016   |   Inventor(s): Chad Heatwole
Keywords(s):  
Category(s): Copyright, Informatics, Research Tools
Congenital and Childhood Myotonic Dystrophy Research Survey: Instrument for Children Ages 5 to 7
This is a disease-specific Patient-reported outcome measure for patients with congenital, childhood-onset, or juvenile myotonic dystrophy type-1. This instrument was developed and validated through the outcome measures laboratory at the University of Rochester and based on original questions developed for adult myotonic dystrophy patients (also see...
Published: 6/30/2016   |   Inventor(s): Chad Heatwole, Nicholas Johnson, Joanna Heatwole
Keywords(s):  
Category(s): Copyright, Informatics, Research Tools
Congenital and Childhood Myotonic Dystrophy Health Index: Instrument for Children Ages 8 to 11
This is a disease-specific Patient-reported outcome measure for patients with congenital, childhood-onset, or juvenile myotonic dystrophy type-1. This instrument was developed and validated through the outcome measures laboratory at the University of Rochester and based on original questions developed for adult myotonic dystrophy patients (also see...
Published: 6/30/2016   |   Inventor(s): Chad Heatwole, Nicholas Johnson
Keywords(s):  
Category(s): Copyright, Informatics, Research Tools
Congenital and Childhood Myotonic Dystrophy Health Index: Instrument for Children Ages 12 to 17
This is a disease-specific patient-reported outcome measure for patients with congenital, childhood-onset, or juvenile myotonic dystrophy type-1. This instrument was developed and validated through the outcome measures laboratory at the University of Rochester and based on original questions developed for adult myotonic dystrophy patients (also see...
Published: 6/30/2016   |   Inventor(s): Chad Heatwole, Nicholas Johnson
Keywords(s):  
Category(s): Copyright, Informatics, Research Tools
Congenital and Childhood Myotonic Dystrophy Health Index: Parent Proxy Instrument
This is a disease-specific proxy reported outcome measure for patient with congenital, childhood-onset, or juvenile myotonic dystrophy type-1. This instrument was developed and validated through the outcome measures laboratory at the University of Rochester and based on original questions developed for adult myotonic dystrophy patients (also see UR...
Published: 6/30/2016   |   Inventor(s): Chad Heatwole, Nicholas Johnson
Keywords(s):  
Category(s): Copyright, Informatics, Research Tools
Preoperative Planning Document To Facilitate Correlation of IVUS and CT Scan Measurements For Placement Of IVUS-Guided IVC Filters
Preoperative planning document for the single puncture intravasular ultrasound (IVUS) guided bedside placement of IVC filters. Application Pulmonary Embolism (PE) has been reported in over 350,000 patients per year, with an estimated annual mortality rate of 240,000. Vena cava filtration is being used as an effective means of prophylaxis against PE...
Published: 3/9/2015   |   Inventor(s): David Gillespie, Sean Hislop
Keywords(s):  
Category(s): Copyright, Informatics, Research Tools
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