Search Results - diagnostic

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A Low Cost Device for the Detection of Prostate Cancer in Real Time
An inexpensive device for early detection of prostate cancer.Problem Solved by This TechnologyCurrent Digital Rectal Exams and chemical screening methods, such as PSA, provide statistically inadequate detection of early prostate cancer development. Moreover, these modalities provide no information relating to the location or the extent of malignanc...
Published: 9/3/2014   |   Inventor(s): Stephen Arnold, Vikram Dogra, Navalgund Rao
Keywords(s): Cancer, Diagnostic, Instrument, Instrumentation, Medical Device, Oncology, Prostate, Ultrasound, Ultrasound Imaging
Category(s): Imaging
Methods For Determining The Presence Or Risk Of Developing Facioscapulohumeral Dystrophy (FSHD)
ApplicationsThis technology provides a DNA-based diagnostic method to determine the presence or the susceptibility of developing Facioscapulohumeral Dystrophy (FSHD) and also a method to treat FSHD.AdvantagesCurrently, the diagnostic test for FSHD1 requires pulse-field gel electrophoresis and Southern blotting to detect the contraction of the D4Z4 ...
Published: 7/19/2012   |   Inventor(s): Al-Rabi Tawil, Stephen Tapscott, Linda Geng, Silvere Van Der Maarel
Keywords(s): Diagnostic, Musculoskeletal
Category(s): Diagnostic
Strong Vision Equation for Enhanced Zyoptix Outcome
The present invention is an algorithm that provides better predictability of postoperative refractive error following customized LASIK treatment for myopia.Applications: The Strong Vision Method provides a superior treatment outcome following customized LASIK surgery by further compensating the effect of higher order aberrations on postoperative ey...
Published: 7/19/2012   |   Inventor(s): Manoj Venkiteshwar, Scott Macrae
Keywords(s): Algorithm, Diagnostic, Ophthalmology, Software, Vision
Category(s): Therapeutic, Optics
A Novel Approach to S.mutans Diagnostics, Therapeutic Intervention and Vaccines
Brief Description:Streptococcus mutans (S.mutans) is a major pathogen commonly found in the human oral cavity and is associated with dental caries. Dissemination of oral bacteria into the bloodstream is very common in patients subjected to dental procedures. S.mutans, if presents in the bloodstream, is suspected as a leading causative agent of card...
Published: 5/26/2011   |   Inventor(s): Jacqueline Abranches, Jose Lemos, Robert Burne
Keywords(s): Antibacterial, Caries, Dental, Diagnostic, Endocarditis, Gene, Infection, Infectious Disease, Oral
Category(s): Therapeutic
Retinal Imaging with Adaptive Optics Optical Coherence Tomography (AO-OCT)
Adaptive optics is used in optical coherence tomography (OCT) to provide very high axial resolution in a non-invasive "optical sectioning" technique for imaging at various depths within living human tissue. In the current commercial application of OCT for retinal imaging, the transverse resolution is limited by the intrinsic ocular aberra...
Published: 6/17/2009   |   Inventor(s): Donald Miller, Junle Qu, Ravi Jonnal, Karen Thorn
Keywords(s): Diagnostic, in vivo, Ophthalmology
Category(s): Diagnostic, Optics, Surgical/Medical Device
Improving Vision and the Resolution of Retinal Images by Measuring and Correcting the Wave Aberration of the Eye
This describes the use of wavefront measurement and adaptive optics to correct all the aberrations of the human eye.ApplicationsWavefront measurement of all the aberrations in the human eye can make possible correction of vision which goes beyond conventional spectacles and contact lenses. This correction of higher order aberrations can be applie...
Published: 6/17/2009   |   Inventor(s): David Williams, Junzhong Liang
Keywords(s): Diagnostic, Ophthalmology
Category(s): Diagnostic
Pediatric Blood Pressure Screening Wheel
Applications:This is a copyrighted screening wheel with potential for widespread use in screening for high blood pressure in children.Advantages:The current method for determining if a child has elevated blood pressure is very cumbersome. It involves plotting a height percentile on a CDC growth chart and then looking at a complicated table for the...
Published: 6/17/2009   |   Inventor(s): Megan Rashid
Keywords(s): Diagnostic, Pediatric
Category(s): Therapeutic
Mouse Model of Osteoarthritis: Over-Expression of Smurf2 in Cartilage to Induce Disease and Over-expression of Smurf1 as a Potential Therapeutic Strategy
Applications:We have generated col2-promoter-Smad ubiquitin regulatory factor2 (col2-Smurf2) transgenic mice which possess a loss of TGFß signaling and display each of above characteristics, thus displaying a phenotype more representative of the disease process. Furthermore, the over-expression of Smurf2 in cartilage that has been induced in...
Published: 6/17/2009   |   Inventor(s): Randy Rosier, Michael Zuscik, Qiugian Wu, Edward Schwarz
Keywords(s): Diagnostic, Therapy
Category(s): Research Tools
Monoclonal Antibodies to von Willebrand Factor Propolypeptide (VWFpp)
ApplicationsThe invention offers monoclonal antibodies against VWFpp as a diagnostic for von Willebrand disease. VWFpp is stored only in the endothelial cell and release of this protein may serve as marker for endothelial cell damage of von Willebrand disease.Advantagesvon Willebrand disease has very mild signs and the condition can be difficult to...
Published: 5/5/2009   |   Inventor(s): Philip Fay, Betsy Ohlsson-Wilhelm
Keywords(s): Diagnostic, Peptide
Category(s): Diagnostic
Non-Invasive in-vivo Imaging of Mechanoreceptors in Human Skin Using Confocal Microscopy
Applications:This invention relates to a technique for non-invasive in vivo imaging of the sensory nerve endings in the skin or Meissner's corpuscles using confocal microscopy.Advantages:Assessment of sensory nerve endings in the skin (Meissner's corpuscles) by means of invasive punch skin biopsy from the palmar surface of the hand or fingers or t...
Published: 5/5/2009   |   Inventor(s): David Herrmann, Jay Eastman, Christi Alessi-Fox, Neil Boger
Keywords(s): Dermatology, Diagnostic, Imaging, Software
Category(s): Diagnostic
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