Search Results - diagnostic

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Compact, Portable (Hand-Held) Wavefront Sensor

Applications: The present invention is a compact, portable (hand-held) wavefront sensor. It is composed of a double path dichrotic filter, a beam splitter, and a dual, unequal wavelength illumination arranged in a system able to measure ocular wave aberrations. Applications include: - Vision screening of infants and children. - Measurement...

Published: 2/1/2024 | Inventor(s): Geunyoung Yoon

Keywords(s): Diagnostic, Ophthalmology, Software, Vision

Category(s): Diagnostic

Photoacoustic Imaging Using a Versatile Acoustic Lens

Applications:Photoacoustic imaging (also called optoacoustic or thermoacoustic imaging) has the potential to image animal or human organs with simultaneous high contrast and high spatial resolution. The photoacoustic signal is small and needs a mechanism to focus it on an image plane without degradation. This technology improves the signal to noise...

Published: 10/5/2023 | Inventor(s): Vikram Dogra, Navalgund Rao, Wayne Knox

Keywords(s): Cancer, Diagnostic, Instrument, Instrumentation, Medical Device, Oncology, Prostate, Ultrasound, Ultrasound Imaging

Category(s): Imaging

CariesPredict

Applications:The present invention relates to antibodies, binding portions or probes to the glucosyl-transferase enzyme and uses of these agents for detecting the glucosyltransferase enzyme in a sample for diagnosing dental caries in a patients, or for diagnosing predisposition of a child to early childhood caries.Advantages:An aspect of this invention...

Published: 5/23/2023 | Inventor(s): William Bowen, Anne Vacca Smith, Robert Berkowitz

Keywords(s): Antibody, Dental, Diagnostic, Oral

Category(s): Diagnostic

Methods For Determining The Presence Or Risk Of Developing Facioscapulohumeral Dystrophy (FSHD)

ApplicationsThis technology provides a DNA-based diagnostic method to determine the presence or the susceptibility of developing Facioscapulohumeral Dystrophy (FSHD) and also a method to treat FSHD.AdvantagesCurrently, the diagnostic test for FSHD1 requires pulse-field gel electrophoresis and Southern blotting to detect the contraction of the D4Z4 repeats,...

Published: 8/14/2023 | Inventor(s): Al-Rabi Tawil, Stephen Tapscott, Linda Geng, Silvere Van Der Maarel, Lauren Snider, Richard Lemmers

Keywords(s): Diagnostic, Musculoskeletal

Category(s): Diagnostic

Strong Vision Equation for Enhanced Zyoptix Outcome

The present invention is an algorithm that provides better predictability of postoperative refractive error following customized LASIK treatment for myopia.Applications: The Strong Vision Method provides a superior treatment outcome following customized LASIK surgery by further compensating the effect of higher order aberrations on postoperative eyes....

Published: 2/14/2024 | Inventor(s): Manoj Venkiteshwar, Scott Macrae

Keywords(s): Algorithm, Diagnostic, Ophthalmology, Software, Vision

Category(s): Therapeutic, Optics

Retinal Imaging with Adaptive Optics Optical Coherence Tomography (AO-OCT)

Adaptive optics is used in optical coherence tomography (OCT) to provide very high axial resolution in a non-invasive "optical sectioning" technique for imaging at various depths within living human tissue. In the current commercial application of OCT for retinal imaging, the transverse resolution is limited by the intrinsic ocular aberrations...

Published: 3/20/2024 | Inventor(s): Donald Miller, Junle Qu, Ravi Jonnal, Karen Thorn

Keywords(s): Diagnostic, in vivo, Ophthalmology

Category(s): Diagnostic, Optics, Surgical/Medical Device

Pediatric Blood Pressure Screening Wheel

Applications:This is a copyrighted screening wheel with potential for widespread use in screening for high blood pressure in children.Advantages:The current method for determining if a child has elevated blood pressure is very cumbersome. It involves plotting a height percentile on a CDC growth chart and then looking at a complicated table for the...

Published: 5/23/2023 | Inventor(s): Megan Rashid

Keywords(s): Diagnostic, Pediatric

Category(s): Therapeutic

Mouse Model of Osteoarthritis: Over-Expression of Smurf2 in Cartilage to Induce Disease and Over-expression of Smurf1 as a Potential Therapeutic Strategy

Applications:We have generated col2-promoter-Smad ubiquitin regulatory factor2 (col2-Smurf2) transgenic mice which possess a loss of TGFß signaling and display each of above characteristics, thus displaying a phenotype more representative of the disease process. Furthermore, the over-expression of Smurf2 in cartilage that has been induced in...

Published: 5/23/2023 | Inventor(s): Randy Rosier, Michael Zuscik, Qiugian Wu, Edward Schwarz

Keywords(s): Diagnostic, Therapy

Category(s): Research Tools

Monoclonal Antibodies to von Willebrand Factor Propolypeptide (VWFpp)

ApplicationsThe invention offers monoclonal antibodies against VWFpp as a diagnostic for von Willebrand disease. VWFpp is stored only in the endothelial cell and release of this protein may serve as marker for endothelial cell damage of von Willebrand disease.Advantagesvon Willebrand disease has very mild signs and the condition can be difficult to...

Published: 5/23/2023 | Inventor(s): Philip Fay, Betsy Ohlsson-Wilhelm

Keywords(s): Diagnostic, Peptide

Category(s): Diagnostic

Non-Invasive in-vivo Imaging of Mechanoreceptors in Human Skin Using Confocal Microscopy

Applications:This invention relates to a technique for non-invasive in vivo imaging of the sensory nerve endings in the skin or Meissner's corpuscles using confocal microscopy.Advantages:Assessment of sensory nerve endings in the skin (Meissner's corpuscles) by means of invasive punch skin biopsy from the palmar surface of the hand or fingers or the...

Published: 2/14/2024 | Inventor(s): David Herrmann, Jay Eastman, Christi Alessi-Fox, Neil Boger

Keywords(s): Dermatology, Diagnostic, Imaging, Software

Category(s): Diagnostic