Monoclonal Antibodies to von Willebrand Factor Propolypeptide (VWFpp)

Brief Description

Applications

The invention offers monoclonal antibodies against VWFpp as a diagnostic for von Willebrand disease. VWFpp is stored only in the endothelial cell and release of this protein may serve as marker for endothelial cell damage of von Willebrand disease.

 

Advantages

von Willebrand disease has very mild signs and the condition can be difficult to diagnose. The common blood test for von Willebrand disease is the measurement of VWF antigen. The present invention offers an alternative method by measuring VWFpp, adding further accuracy to identify the disease.

 

URV Reference Number: 6-1399

Patent Information:
Category(s):
Diagnostic
For Information, Contact:
Daisy Bunbury
Licensing Manager
University of Rochester
 
Inventors:
Philip Fay
Betsy Ohlsson-Wilhelm
Keywords:
Diagnostic
Peptide