A Mouse Line that Lacks Phosphoinositide

Brief Description

Applications

The invention generates a mouse line that is Phosphoinositide 3-Kinase g-deficient. The mouse model can be used in target validation assays for arthritis, asthma, septic shock, and atherosclerosis.

Advantages

The mouse model can provide information as to which human disease might benefit from drugs designed to inhibit Phosphoinositide 3-Kinase g.

Direct Link:

http://rochester.technologypublisher.com/technology/2791

Category(s):

Research Tools

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For Information, Contact:

Matan Rapoport

Licensing Associate

University of Rochester

585.276.6600

matan.rapoport@rochester.edu

Inventors:

Dianqing (Dan) Wu

Keywords:

Research Tool