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Second Harmonic Generation (SHG) and Multiphoton Microscopies Predict and Identify Untreatable Lung Fibrosis

Background When a patient detects a lump in the breast or a screening mammogram detects a density, a core needle biopsy is performed and the resultant cylinder of tissue is traditionally sectioned, mounted on a slide, H+E stained, and viewed by a pathologist to determine if a patient has cancer versus something more benign. If cancer is diagnosed,...

Published: 8/5/2022 | Inventor(s): Seth Perry, Edward Brown III, Robert Kottmann, Patricia Sime, Jesse Sharpe

Keywords(s):

Category(s): Diagnostic

LDH Inhibitors as Treatment for Fibrotic Disorders

One aspect of the disclosure relates to methods of treating a fibrotic condition in an individual. The methods include administering to an individual having a fibrotic condition an effective amount of a lactic dehydrogenase (LDH) inhibitor, wherein the fibrotic condition involves an internal organ or tissue, or ocular tissue, and said administering...

Published: 11/21/2022 | Inventor(s): Robert Kottmann, Patricia Sime, Richard Phipps

Keywords(s):

Category(s): Therapeutic