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Second Harmonic Generation (SHG) and Multiphoton Microscopies Predict and Identify Untreatable Lung Fibrosis
Background When a patient detects a lump in the breast or a screening mammogram detects a density, a core needle biopsy is performed and the resultant cylinder of tissue is traditionally sectioned, mounted on a slide, H+E stained, and viewed by a pathologist to determine if a patient has cancer versus something more benign. If cancer is diagnosed,...
Published: 5/23/2023
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Inventor(s):
Seth Perry
,
Edward Brown III
,
Robert Kottmann
,
Patricia Sime
,
Jesse Sharpe
Keywords(s):
Category(s):
Diagnostic
LDH Inhibitors as Treatment for Fibrotic Disorders
One aspect of the disclosure relates to methods of treating a fibrotic condition in an individual. The methods include administering to an individual having a fibrotic condition an effective amount of a lactic dehydrogenase (LDH) inhibitor, wherein the fibrotic condition involves an internal organ or tissue, or ocular tissue, and said administering...
Published: 5/7/2024
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Inventor(s):
Robert Kottmann
,
Patricia Sime
,
Richard Phipps
Keywords(s):
Category(s):
Therapeutic