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Septin inhibitors for treatment of cancer

Background Effective therapeutic options are limited for the treatment of liver, lung, renal, ovarian, endometrial and pancreatic cancer. Successive second- and third-line therapies do not add meaningful responses besides adding numerous life-debilitating toxicities. In order to improve the survival rate of patients diagnosed with these lethal malignancies,...

Published: 8/14/2023 | Inventor(s): Richard Moore, Rakesh Singh, Kyu Kwang Kim, Rachael Turner

Keywords(s):

Category(s): Therapeutic

URML-3881, a Novel MEK Inhibitor for the Treatment of Cancers

Provided herein, are compounds, compositions, and methods of treatment of cancers using an inhibitor of MAPK/ERK Kinase (MEK), in particular hydrazine derivatives.

Published: 10/5/2023 | Inventor(s): Richard Moore, Rakesh Singh, Rachael Turner, Kyu Kwang Kim, Negar Khazan

Keywords(s):

Category(s): Therapeutic