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Reorganization of Arenavirus Genome for Development of Novel Arenavirus Live-Attenuated Vaccines (LAV)
Disclosed are compositions and methods related to recombinant arenaviruses and their use in vaccines for the treatment or prevention of an arenavirus infection.
Published: 10/28/2024   |   Inventor(s): Juan Carlos De La Torre, Luis Martinez-Sobrido, Masaharu Iwasaki, Beatrice Cubitt
Keywords(s):  
Category(s): Vaccines
Development of Arenavirus Vaccines through Codon Deoptimization
A novel strategy for developing live-attenuated arenavirus vaccines. Problem Solved by the TechnologyArenaviruses have a significant impact on public health and pose a credible threat to biodefense.There are four arenaviruses that cause severe hemorrhagic fever in humans (Lassa virus, endemic to Africa; and Machupo, Junin, and Guanarito viruses endemic...
Published: 10/28/2024   |   Inventor(s): Luis Martinez-Sobrido, Juan Carlos De La Torre
Keywords(s):  
Category(s): Vaccines