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Activated Protein C Inhibits p53-Mediated Apoptosis and Acts as a Cell Survival Factor in the Central Nervous System

Applications:Activated protein C (APC), pro-drug, and/or a variant thereof may be used as an inhibitor of apoptosis or cell death and/or a cell survival factor, especially for stressed or injured cells or tissues of the nervous system including subjects with neurodegenerative disorders.Advantages:Novel biological functions (e.g., neuroprotection) can...

Published: 12/5/2023 | Inventor(s): Berislav Zlokovic, John Griffin

Keywords(s): Aging, Alzheimer's, Neurological, Therapy

Category(s): Therapeutic