Compounds Enhancing Platelet Production

Brief Description
Applications:
The invention identifies novel compounds that enhance platelet production in cases where platelet number is low, such as after ionizing radiation exposure, chemotherapy, and autoimmunity.

Advantages:
Existing therapy such as TPO (thrombopoietin) only enhances production of megakaryocytes but does not directly enhance the production of platelets.
Patent Information:
Title Country Patent No. Issued Date
Use of Electrophilic Compounds for Inducing Platelet Production or Maintaining Platelet Function United States 9,012,439 4/21/2015
Category(s):
Therapeutic
For Information, Contact:
Weimin Kaufman
Licensing Manager
University of Rochester
585.276.6608
weimin.kaufman@rochester.edu
Inventors:
Richard Phipps
Jamie O'Brien (Bernard)
Keywords:
Blood
Radiology
Therapy
Cell Signalling