Transcutaneous Immunization Against Papillomavirus Disease

Brief Description
Brief Description:
This invention is a method of vaccinating against human papillomavirus (HPV) by using papillomavirus ?virus-like particles? transcutaneously to induce an immune response to the virus.

Applications:
Papiloma viruses constitute a group of DNA viruses that induce both lytic infections and either benign or malignant tumors. Papiloma viruses infect cutaneous, genital, oral, and respiratory epithelia in a tissue-specific manner. Infection with HPV has been associated closely with plantar warts, condylomata acuminata (anogenital warts), and premalignant and malignant lesions of the cervical squamous epithelium.

Advantages:
The ease of administration makes this useful for large-scale field administration, for use with pediatric or elderly patients as well as patients in Third-World populations.
Patent Information:
Title Country Patent No. Issued Date
Transcutaneous Immunization Against Papillomavirus with Papillomavirus Virus-like Particles United States 7,247,433 7/24/2007
Category(s):
Vaccines
For Information, Contact:
Matan Rapoport
Licensing Associate
University of Rochester
585.276.6600
matan.rapoport@rochester.edu
Inventors:
Robert Rose
Keywords:
Vaccine