High Affinity Binding Proteins to Integrins
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This technology is related to the development of high affinity binding proteins to specific integrin proteins highly associated with cancer metastasis. Applications of these targeting molecules include tumor imaging, targeted tumor therapy, and targeted gene delivery.
These molecules are more stable, easier to make, and more amenable to protein engineering techniques than short peptides and antibodies.
avB3 Integrin-Binding Polypeptide Monobodies and Their Use
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University of Rochester
Julie Richards Gunzler
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