Search Results - cell signalling

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Human KC-NL Crosstalk Subversion by HCV
Applications:The invention has developed an in vitro culture system based on the isolation of human Kupffer cells (KC) and natural Killer Cells (NK) from the donated liver grafts. The model can be used for the identification of drug targets of viral hepatitis, and for testing drugs and biologics.Advantages:The model uses human cells directly from the...
Published: 6/17/2009   |   Inventor(s): Mark Orloff, Ian Nicholas Crispe
Keywords(s): Cell Signalling, Immunology, Research Tool, Therapy
Category(s): Research Tools
Reagents Identifying PPARγ Isoforms
Applications:Reagents can be used for commercial western blot/ELISA/Flow Cytometry.Advantages:Currently there are no proven reagents that distinguish PPAR gamma isoforms.
Published: 6/17/2009   |   Inventor(s): Richard Phipps
Keywords(s): Cell Signalling, Therapy
Category(s): Research Tools
Human Biliverdin Reductase is a New Member of the Insulin Receptor Substrate Family with Serine/Threonine/Tyrosine Kinase Activity
Applications:Human biliverdin reductase (BVR) is an evolutionary conserved soluble enzyme that was originally characterized in the context of its reductase activity (conversion of biliverdin to bilirubin) and more recently shown to possess serine/threonine/tyrosine kinase activity. The present work demonstrates that this dual kinase activity of BVR...
Published: 6/17/2009   |   Inventor(s): Mahin Maines
Keywords(s): Cell Signalling, Therapy
Category(s): Therapeutic