Search Results - berislav zlokovic

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Activated Protein C Inhibits p53-Mediated Apoptosis and Acts as a Cell Survival Factor in the Central Nervous System
Applications:Activated protein C (APC), pro-drug, and/or a variant thereof may be used as an inhibitor of apoptosis or cell death and/or a cell survival factor, especially for stressed or injured cells or tissues of the nervous system including subjects with neurodegenerative disorders.Advantages:Novel biological functions (e.g., neuroprotection) can...
Published: 4/29/2019   |   Inventor(s): Berislav Zlokovic, John Griffin
Keywords(s): Aging, Alzheimer's, Neurological, Therapy
Category(s): Therapeutic
Novel Small Molecules to Treat Alzheimer’s Disease
Small compounds that inhibit the uptake of amyloid-β into the brain.Problem Solved by this TechnologyThere are over 5 million Americans with Alzheimer's disease (AD). Current therapies target only symptoms and do not inhibit or reverse the cause and progression of the disease. Recent research has identified the transport mechanism of the neurotoxic...
Published: 8/5/2014   |   Inventor(s): Berislav Zlokovic, Rashid Deane, Benjamin Miller
Keywords(s):  
Category(s): Therapeutic