Applications:Change in the mechanical properties of tissue is a possible marker of disease. In this technology, the imaging modality of sonoelastography is used to examine the stiffness of tissue to discriminate normal from abnormal tissue types (such as carcinomas) by visualizing shear wave interference pattern motion (termed “crawling waves”). The mathematical algorithms can be readily translated to existing commercial ultrasound scanners equipped with Doppler imaging functionality.Advantages:The technique provides real time quantitative imaging and analysis of tissue stiffness, which is known to change with pathologic state. The technique transforms the spatially varying shear wave vibrational fields into localized maps of quantitative elastic parameters, in the form of shear velocity or moduli distributions. Other techniques proposed earlier do not allow real-time imaging due to algorithm complexity.