Methods for Identifying, Diagnosing, and Predicting Survival of Lymphomas

The present invention discloses methods for identifying, diagnosing, and predicting survival in a lymphoma or lymphoproliferative disorder on the basis of gene expression patterns. The invention discloses a novel microarray, the Lymph Dx microarray, for obtaining gene expression data from a lymphoma sample. The invention also discloses a variety of methods for utilizing lymphoma gene expression data to determine the identity of a particular lymphoma and to predict survival in a subject diagnosed with a particular lymphoma. This information is useful in developing the appropriate therapeutic approach for use with a particular subject.

URV Reference Number: 6-1850
Patent Information:
Title Country Patent No. Issued Date
Methods for Identifying, Diagnosing, and Predicting Survival of Lymphomas United States 7,711,492 5/4/2010
Methods for identifying, diagnosing, and predicting survival of lymphomas United States 8,131,475 3/6/2012
Category(s):
Diagnostic
For Information, Contact:
Blaze Pharoah
Licensing Manager
University of Rochester
585-276-6600
blaze_pharoah@urmc.rochester.edu
Inventors:
Richard Fisher
George Wright
Sandeep Dave
Bruce Tan
Louis Staudt
John Powell
Wyndham Wilson
Elaine Jaffe
Wing Chan
Timothy Greiner
Dennis Weisenburger
James Armitage
Kai Fu
Lisa Rimza
Thomas Miller
Thomas Grogan
Elias Campo Guerri
Silvia Bea
Itziar Salaverria
Armando Lopez-Guillermo
Emilio Montserrat Costa
Victor Moreno
Andreas Zettl
German Ott
Hans-Konrad Muller-Hermelink
Andreas Rosenwald
Julie Vose
Randy Gascoyne
Joseph Connors
Erlend Smeland
Stein Kvaloy
Harald Holte
Jan Delabie
Andrew Lister
Keywords: