Search Results - robert+pierce

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Mouse Model of Chronic Viral Hepatitis
Applications:The invention generates a novel mouse model of acute and chronic T cell mediated hepatitis, which shares some important features with viral hepatitis in man. The mouse model is valuable in identifying drug targets for viral hepatitis.Advantages:The mouse model is driven directly by CD8+ T cell and results from the recognition of an antigen...
Published: 6/17/2009   |   Inventor(s): Ian Nicholas Crispe, Robert Pierce
Keywords(s): Gastrointestinal, Hepatic, Mouse, Research Tool, Viral disease
Category(s): Research Tools
Polyketal Nanoparticles (PKNs): a Novel Macrophage-Selective Drug-Delivery System
ApplicationsPolykeltal nanoparticles (PKNs) represent a novel and effective drug delivery vehicle, which appear to target macrophages selectively. Currently, PKNs can be used to incorporate any lipophilic pharmaceutical or lipophilic peptide. Inventors are now working on adapting the reverse-phase emulsion technique which will allow for the incorporation...
Published: 6/17/2009   |   Inventor(s): Niren Murthy, Bali Pulendran, Robert Pierce
Keywords(s): Therapy
Category(s): Therapeutic