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HSA LR Mice (Mouse Model of Myotonic Dystrophy)
ApplicationsThe invention offers a transgenic mouse model for myotonic dystrophy. This mouse model expresses expanded CUG repeats and develops myotonia and myopathy. This model can be utilized to examine interactions between the loss- and gain-of-function effects of the mutation and to investigate the mechanism for nuclear retention and toxicity of...
Published: 10/28/2024
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Inventor(s):
Charles Thornton
Keywords(s):
Disease Model
,
Mouse
,
Musculoskeletal
,
Research Tool
Category(s):
Research Tools