Search Results - disease+model

1 Results Sort By:
HSA LR Mice (Mouse Model of Myotonic Dystrophy)
ApplicationsThe invention offers a transgenic mouse model for myotonic dystrophy. This mouse model expresses expanded CUG repeats and develops myotonia and myopathy. This model can be utilized to examine interactions between the loss- and gain-of-function effects of the mutation and to investigate the mechanism for nuclear retention and toxicity of...
Published: 6/17/2009   |   Inventor(s): Charles Thornton
Keywords(s): Disease Model, Mouse, Musculoskeletal, Research Tool
Category(s): Research Tools