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HSA LR Mice (Mouse Model of Myotonic Dystrophy)

ApplicationsThe invention offers a transgenic mouse model for myotonic dystrophy. This mouse model expresses expanded CUG repeats and develops myotonia and myopathy. This model can be utilized to examine interactions between the loss- and gain-of-function effects of the mutation and to investigate the mechanism for nuclear retention and toxicity of...

Published: 8/14/2023 | Inventor(s): Charles Thornton

Keywords(s): Disease Model, Mouse, Musculoskeletal, Research Tool

Category(s): Research Tools