Search Results - benjamin+miller

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RNA-Targeted Small Molecules as Potential Antiviral Therapy (HIV, SARS etc)

Brief Description: A high error rate of HIV -I reverse transcriptase coupled with a fast replication cycle associated with HIV -1 favors rapid development and selection of drug resistant strains. Therefore, identification of small molecules capable of inhibiting viral components necessary for HIV -1 proliferation continues to be of great importance....

Published: 9/19/2023 | Inventor(s): Benjamin Miller, Brian Mcnaughton, Peter Gareiss, Joseph Wedekind

Keywords(s): AIDS, HIV, Small Molecule, Therapy

Category(s): Therapeutic

Novel, Synthetic Peptides that Inhibit the Formation of Tight Junctions

Background Current methods of vaccination primarily rely on intramuscular, subcutaneous, and intradermal injection of antigens. These vaccination routes, while effective, require medical personnel to deliver, generate biohazards (sharps) requiring costly disposal, and cause patients pain and anxiety. This has fueled research efforts to identify “needle-free”...

Published: 2/14/2024 | Inventor(s): Benjamin Miller, Lisa Beck, Matthew Brewer

Keywords(s):

Category(s): Therapeutic

Carbohydrate-targeted Therapeutic Agents, Diagnostics, and Sensors

Applications:Carbohydrates represent a particularly enticing and important challenge to the organic chemist interested in molecular recognition. In addition to their role in addressing the fundamental problem of understanding binding and selectivity, novel carbohydrate receptors have significant potential as tools in the rapidly evolving field of glycomics,...

Published: 2/14/2024 | Inventor(s): Benjamin Miller, Prakash Palde, Peter Gareiss

Keywords(s): Research Tool

Category(s): Research Tools

Modulating Melanin Expression

Compounds which can induce melanin expression to aid in certain clinical indications or for cosmetic purposes.Problem Solved by This TechnologyMelanin is important for disease prevention, because it absorbs ultraviolet light in the UVB and UVA spectrum. This protects keratinocytes from the mutagenic effects of sunlight. In addition, melanin has a social...

Published: 2/14/2024 | Inventor(s): Benjamin Miller, Brian Mcnaughton, Peter Gareiss, Glynis Scott

Keywords(s): Cancer, Dermatology, Oncology, Small Molecule, Therapy

Category(s): Therapeutic