Automated Placental Measurement

Brief Description: The technology disclosed herein is a new approach towards automated measurements of the intrauterine environment through placental imaging and histology.

 

Applications: This technology is a method for analyzing the placenta and histology slides of placental tissue. The methods teach a process for extracting medically significant information from digital images of placental tissue by processing the image through a specific mathematical algorithm. Results from the placenta analysis are then correlated with data on health outcomes in infants, children, or adults and are used to assess future physiological risks to a patient.

 

Advantages: The placenta, the key organ upon which the fetus is entirely dependent on, grows in a branching fashion similarly to the growth of a tree and its branches. Unfortunately, routine pathology slide review has poor reliability in distinguishing the major patterns of placental branching and morphogenesis. As the evidence continues to surface that lifelong health risks appear to be correlated with birth weight, the importance of placental growth and development as the principal non-genetic contributor to fetal growth has grown. Therefore, a reliable and automated assessment tool performed on routine stained placental slides is needed to help physicians understand how intrauterine stressors control placental wellbeing. This technology provides just that, an automated, reliable, and inexpensive method of measurement of placental vascular growth through placental imaging and histology to help physicians quickly and dependably understand each patient’s individual intrauterine stressors to assess potential physiological risks.

URV Reference Number: 6-1722
Patent Information:
Title Country Patent No. Issued Date
Automated Placental Measurement United States 8,107,710 1/31/2012
For Information, Contact:
Joynita Sur (URV)
Licensing Manager
University of Rochester
Joynita_Sur@urmc.rochester.edu
Inventors:
Richard Miller
Carolyn Salafia
Keywords: