Search Results - craig jordan

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Parthenolide Derivatives, Methods for Their Preparation and Their Use as Anticancer Agents
Brief Description:The plant-derived natural product parthenolide was recently found to possess potent in vitro and in vivo antitumor activity against leukemia and many other human malignancies, including breast, lung, prostate, liver, brain, pancreas, and bone cancer. This invention describes synthetic methodologies that enable the functionalizatio...
Published: 4/25/2019   |   Inventor(s): Rudi Fasan, Craig Jordan, Joshua Kolev
Keywords(s):  
Category(s): Therapeutic
Novel Melampomagnolide-based Anti-Cancer Drugs and Pro-Drugs that Target Leukemia Stem Cells
Brief Description: Adult acute leukemia is an extremely serious disease, resulting in death for the majority of patients. Despite decades of intensive research, long-term cures are obtained for only approximately 30% of patients. Thus, there is an urgent need for the development of treatment regimens that are more efficacious and less toxic to...
Published: 2/26/2019   |   Inventor(s): Craig Jordan, Shanshan Pei
Keywords(s): Blood, Cancer, Leukemia
Category(s): Therapeutic